ArticleJournal of stroke2019
The Aspirations of Direct Aspiration for Thrombectomy in Ischemic Stroke: A Critical Analysis.
Article in Journal of stroke, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Distal medium vessel occlusions in acute ischaemic stroke - Stent retriever versus direct aspiration: A systematic review and meta-analysis.European stroke journal · 2023Pooled it
- Susceptibility Vessel Sign and Intravenous Alteplase in Stroke Patients Treated with Thrombectomy : A Secondary Analysis of the SWIFT DIRECT Trial.Clinical neuroradiology · 2025Trial
- Thrombus iodine-based perviousness is associated with recanalisation and functional outcomes in endovascular thrombectomy.Stroke and vascular neurology · 2025Article
- Predictors and Outcomes of Excellent Recanalization Versus Successful Recanalization After Thrombectomy in Proximal and Distal Medium Vessel Occlusion Strokes: A Multinational Study.Stroke (Hoboken, N.J.) · 2024Article
- Outcomes and Complications Associated with Mechanical Thrombectomy in the Treatment of Acute Ischemic Stroke.Cardiology and cardiovascular medicine · 2024Article
- Robust Collaterals Are Independently Associated With Excellent Recanalization in Patients With Large Vessel Occlusion Causing Acute Ischemic Stroke.Stroke (Hoboken, N.J.) · 2024Article
- What You Always Wanted to Know about Endovascular Therapy in Acute Ischemic Stroke but Never Dared to Ask: A Comprehensive Review.Reviews in cardiovascular medicine · 2022Review
- The Q and A-The MIVI Q Catheters for Aspiration Thrombectomy-Initial Experience from London.Journal of clinical medicine · 2021Article
- Dose-Response Relationship and Threshold Drug Dosage Identification for a Novel Hybrid Mechanical-Thrombolytic System with an Ultra-Low Dose Patch.Cellular and molecular bioengineering · 2021Article
- Revascularization Outcome Prediction for A Direct Aspiration-First Pass Technique (ADAPT) from Pre-Treatment Imaging and Machine Learning.Brain sciences · 2021Article
- Characterization of thrombus composition with multimodality CT-based imaging: an in-vitro study.Journal of neurointerventional surgery · 2021Article
- The novel Tenzing 7 delivery catheter designed to deliver intermediate catheters to the face of embolus without crossing: clinical performance predicted in anatomically challenging model.Journal of neurointerventional surgery · 2021Article
- Switch Strategy from Direct Aspiration First Pass Technique to Solumbra Improves Technical Outcome in Endovascularly Treated Stroke.International journal of environmental research and public health · 2021Article
- Thrombus Composition and Efficacy of Thrombolysis and Thrombectomy in Acute Ischemic Stroke.Stroke · 2021Review
- Pathophysiologic and Therapeutic Perspectives Based on Thrombus Histology in Stroke.Journal of stroke · 2020Review
- A Technical Report on the Performance of a New Large Bore Cerebral Aspiration Catheter, the First Results.Cardiovascular and interventional radiology · 2019Article
- Direct Aspiration: Can It Be Aspired?Journal of stroke · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 5 countries.
Funding
Abstract
The treatment of acute ischemic stroke by mechanical thrombectomy has been revolutionary, however most of the clinical trials were done with the use a stent retriever. At the same time, an alternative technique of thrombectomy through direct aspiration with a large bore distal access catheter at the face of the clot is rapidly gaining popularity. Nonetheless, the data supporting this new technique is not yet as mature as that available on stent retrievers. This review is a critical analysis of the evidence supporting the principle of direct aspiration thrombectomy and a discussion of its potential strengths and weaknesses in comparison to the available studies on stent retrievers. While this is by no means a conclusive review, it should serve as a yardstick of where the science is currently, and what are the next trials that are necessary.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.