Evidence map›Paper›PMID 30731081›Full record

ArticleAmerican journal of ophthalmology2019

Rectus Extraocular Muscle Paths and Staphylomata in High Myopia.

Yunping Li, Qi Wei, Alan Le, Bola Ayoub Gawargious, Joseph L Demer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Nasotemporal Asymmetry in Ocular Biometry as a Biomarker for Myopia Progression in Chinese Children.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
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  3. Inferior displacement of the lateral rectus muscle insertion in exotropia with mild V-pattern or vertical deviation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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  8. Mutational screening ofMolecular vision · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yunping LiStein Eye Institute and Department of Ophthalmology, University of California, Los Angeles, Los Angeles, California, USA.
Qi WeiDepartment of Bioengineering, George Mason University, Fairfax, Virginia, USA.
Alan LeStein Eye Institute and Department of Ophthalmology, University of California, Los Angeles, Los Angeles, California, USA.
Bola Ayoub GawargiousDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, USA.
Joseph L DemerStein Eye Institute and Department of Ophthalmology, University of California, Los Angeles, Los Angeles, California, USA; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, USA; Department of Neurology, University of California, Los Angeles, Los Angeles, California, USA; Neuroscience Interdepartmental Program, University of California, Los Angeles, Los Angeles, California, USA; Bioengineering Interdepartmental Program, University of California, Los Angeles, Los Angeles, California, USA. Electronic address: jld@jsei.ucla.edu.
University of California, Los Angeles · USGeorge Mason University · US

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Gregory Darin Field, DAVID S WILLIAMS · 1985 to 2026
$16.8M
BIOMECHANICAL ANALYSIS IN STRABISMUS SURGERYR01EY008313 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH Louis DEMER · 1991 to 2026
$15.0M
NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY008313
6 · The paper itself

Abstract

purposeTo investigate the relationship between displacement of extraocular muscles (EOMs) and staphyloma in high myopia using magnetic resonance imaging (MRI).

designRetrospective case-control study.

methodsSetting: Institutional study. POPULATION: Twenty-nine highly myopic patients (46 eyes), 11 age-matched healthy control subjects (21 eyes), and 34 patients (66 eyes) with sagging eye syndrome. PROCEDURES: MRI was analyzed for aspect ratio (AR) of the ocular cross section, locations of staphylomata and EOMs, and status of superior rectus to lateral rectus (SR-LR) band ligament.

main outcome measuresAssociation between staphylomata with EOM paths and the LR-SR band.

resultsSeveral associations of staphylomata were statistically significant (P < .05). Most staphylomata were superotemporal. Myopic patients with staphyloma had larger ARs in quasi-coronal images than in myopic subjects without staphyloma or normal controls. Compared to patients with high myopia without staphyloma and normal controls, when staphyloma was present, there was more inferior LR displacement, larger LR-globe angle, and larger SR-LR displacement angle than in myopic subjects without staphyloma. Staphyloma in the superotemporal quadrant was associated with greater SR-LR angle than in other quadrants. There were significantly more ruptures of SR-LR band ligament in highly myopic patients with staphyloma than in those without staphyloma.

conclusionsLocal staphylomata in high myopia reflect ocular asphericity and correlate with EOM paths. Myopic staphylomata are associated with inferior displacement of LR path and defect of the LR-SR band ligament.

Indexed as

AdultAgedAxial Length, EyeCase-Control StudiesFemaleHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiddle AgedMyopia, DegenerativeOculomotor MusclesOrbitRetrospective StudiesScleral DiseasesStrabismus

Identifiers

PMID30731081
PMCPMC6511469
OpenAlexW2913471202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.