ArticlePloS one2019
Determination of lead levels in maternal and umbilical cord blood at birth at the Lagos University Teaching Hospital, Lagos.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Blood lead levels ≤10 micrograms/deciliter and executive functioning across childhood development: A systematic review.Neurotoxicology and teratologyPooled it
- Transcriptomic effects of lead on the differentiation of human embryonic stem cells into ectoderm: implication for adverse pregnancy outcomes and neurodevelopmental disorders.Archives of toxicology · 2026Article
- Toxic Trace Element Levels in Maternal and Cord Blood Worldwide and Their Impact on Pregnancy: A Narrative Review.Journal of xenobiotics · 2026Review
- Post-fire soil hazards: recommendations for updated soil testing protocols and clearance thresholds.Journal of exposure science & environmental epidemiology · 2025Review
- Lead and Iron Levels in Maternal and Umbilical Cord Blood in Basrah, Iraq.Sultan Qaboos University medical journal · 2025Article
- Pilot Monitoring of Lead in Umbilical Cord Blood of Newborns Associated With the Use of Glazed Ceramics from Guanajuato, Mexico.Biological trace element research · 2024Article
- Maternal and Umbilical Cord Blood Lead Levels in Selected Informal Settlements in Nairobi, Kenya: A Cross-Sectional Study.Environmental health perspectives · 2024Article
- Blood lead levels in pregnant women and their newborn infants at an Indian teaching hospital.Journal of family medicine and primary care · 2024Article
- Relationship between lead concentration in maternal and umbilical cord blood and some neonatal outcomes in primiparous opium-dependent mothers in Zahedan, Southeast of Iran in 2022.BMC pregnancy and childbirth · 2023Article
- Prenatal blood lead levels and Birth Weight: a Meta-analysis study.Journal of environmental health science & engineering · 2023Review
- The construction and validation of a lead exposure screening tool for pregnant women in Thailand (ThaiL8Is).Heliyon · 2022Article
- Blood Lead Levels among Non-Occupationally Exposed Pregnant Women in Southern Thailand.Toxics · 2022Article
- Maternal Blood Levels of Toxic and Essential Elements and Birth Outcomes in Argentina: The EMASAR Study.International journal of environmental research and public health · 2022Article
- Selected Metal Concentration in Maternal and Cord Blood.International journal of environmental research and public health · 2021Article
- Chronic developmental lead exposure increases μ-opiate receptor levels in the adolescent rat brain.Neurotoxicology · 2021Article
- Blood lead levels in antenatal women and its association with iron deficiency anemia and adverse pregnancy outcomes.Journal of family medicine and primary care · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLead toxicity is a cause of intellectual disability in children and majority of affected children live in developing countries. Its adverse effect on pregnancy outcome has also been documented.
objectivesTo assess the relationship between maternal blood lead levels and umbilical cord blood lead levels in their corresponding newborn infants; to determine factors associated with high blood lead levels and the pregnancy outcome in participants. MATERIALS AND
methodsThis was a cross-sectional descriptive study carried out at a tertiary Teaching Hospital, Lagos, Nigeria. Four hundred and forty pregnant women and their respective newborns delivered at the study centre. Blood samples were obtained from the mothers and umbilical cord of the newborns at delivery and analysed by atomic absorption spectrophotometry. Socio-demographic and obstetric data was obtained by questionnaires administered to the mothers. The anthropometric measurements of the babies were taken at birth and clinical data recorded. Main outcome measures were blood lead levels in mother and baby pair, socio-demographic factors, birth weight, gestational age, length, occipito-frontal circumference.
resultsThe median maternal and umbilical blood lead level was 64.3μg/dl and 39.2μg/dl respectively. The levels were above 5μg/dl in 75.6% and 66.8% of mothers and umbilical cord respectively. There was a strong positive correlation between the maternal and umbilical cord blood lead levels (rs = 0.80). Use of calcium supplements during pregnancy was significantly associated with a lower maternal blood lead level (p = 0.010) while recent painting and renovation of residential accommodation were associated with a higher umbilical cord blood lead level (p = 0.025). There were no statistically significant associations between the maternal and umbilical cord blood lead levels and the gestational age and anthropometry of the newborns at birth.
conclusionsThe blood lead levels in newborns of women residing in Lagos, Nigeria are high and administration of antenatal calcium is associated with lower blood lead levels.
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