ArticlePLoS neglected tropical diseases2019
Serological evidence of infection with dengue and Zika viruses in horses on French Pacific Islands.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Mosquito-borne viral infections: veterinary diagnostic approach with a One Health perspective.Journal of clinical microbiology · 2026Review
- Dengue Virus-Susceptible Animal Models: Research Progress, Core Bottlenecks, and Future Perspectives.Vaccines · 2026Review
- Reconstructing the silent circulation of West Nile Virus in a Caribbean island during 15 years using sentinel serological data.PLoS neglected tropical diseases · 2025Article
- An Update on the Entomology, Virology, Pathogenesis, and Epidemiology Status of West Nile and Dengue Viruses in Europe (2018-2023).Tropical medicine and infectious disease · 2024Review
- Undetection of vector-borne viruses in equids of Galapagos Islands.Frontiers in veterinary science · 2024Article
- Serological and molecular detection of dengue virus in animals: A systematic review and meta-analysis.Le infezioni in medicina · 2024Review
- Serological survey on bovine viral diarrhea virus in man and evaluation of relation with Zika virus-associated microcephaly.Open veterinary journal · 2023Article
- West Nile, Sindbis and Usutu Viruses: Evidence of Circulation in Mosquitoes and Horses in Tunisia.Pathogens (Basel, Switzerland) · 2023Article
- Article
- Serological Evidence of Exposure to Saint Louis Encephalitis and West Nile Viruses in Horses of Rio de Janeiro, Brazil.Viruses · 2022Article
- Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa.The Journal of general virology · 2022Article
- Viral Safety Issues in the Production and Manufacturing of Human Immunoglobulin Preparations from Equine Plasma/Serum.Pharmaceutical chemistry journal · 2022Article
- Novel Assay to Measure Seroprevalence of Zika Virus in the Philippines.Emerging infectious diseases · 2021Article
- Animals as potential reservoirs for dengue transmission: A systematic review.One health (Amsterdam, Netherlands) · 2021Review
- Article
- Evidence of Exposure to USUV and WNV in Zoo Animals in France.Pathogens (Basel, Switzerland) · 2020Article
- Serological Evidence of West Nile and Usutu Viruses Circulation in Domestic and Wild Birds in Wetlands of Mali and Madagascar in 2008.International journal of environmental research and public health · 2020Article
- Strain-Dependent Activity of Zika Virus and Exposure History in Serological Diagnostics.Tropical medicine and infectious disease · 2020Article
- High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel.PLoS neglected tropical diseases · 2019Article
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Authors and funding
13 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
New Caledonia and French Polynesia are areas in which arboviruses circulate extensively. A large serological survey among horses from New Caledonia and French Polynesia was carried out to investigate the seroprevalence of flaviviruses in the horse population. Here, 293 equine sera samples were screened for flaviviruses using a competitive enzyme-linked immunosorbent assay (cELISA). The positive sera were then confirmed using a flavivirus-specific microsphere immunoassay (MIA) and seroneutralization tests. This serosurvey showed that 16.6% (27/163) and 30.8% (40/130) of horses were positive for cELISA tests in New Caledonia and French Polynesia, respectively, but the MIA technique, targeting only flaviviruses causing neuro-invasive infections in humans and horses (i.e. West Nile virus [WNV], Japanese encephalitis virus [JEV] and tick-borne encephalitis virus [TBEV]), showed negative results for more than 85% (57/67) of the cELISA-positive animals. Seroneutralization tests with the main flaviviruses circulating in the South Pacific revealed that 6.1% (10/163; confidence interval [95% CI] 3.0%-11.0%) of sera in New Caledonia and 7.7% (10/130; 95% CI 3.8%-13.7%) in French Polynesia were positive for dengue virus serotype 1 (DENV1) and 4.3% (7/163; 95% CI 1.7%-8.6%) in New Caledonia and 15.4% (20/130, 95% CI 9.7%-22.8%) in French Polynesia were found positive for Zika virus (ZIKV). Seroprevalence of the JEV and WNV flaviviruses on the 293 samples from both island groups were comparatively much lower (less than 2%). This seroprevalence study in the horse population shows that horses can be infected with dengue and Zika viruses and that these infections lead to seroconversions in horses. The consequences of these infections in horses and their role in ZIKV and DENV epidemiological cycles are two issues that deserve further investigation.
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