ArticleThe Journal of urology2019
Baseline Urinary Tract Imaging in Infants Enrolled in the UMPIRE Protocol for Children with Spina Bifida.
Article in The Journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Kidney Morbidity in Pediatric Patients With Spina Bifida.JAMA network open · 2026Article
- Diagnostic Test Characteristics of Ultrasound-Based Hydronephrosis for Chronic Kidney Disease in Children and Adolescents With Myelomeningocele: Results From the UMPIRE and National Spina Bifida Patient Registry Cohort Studies.The Journal of urology · 2025Article
- Paying to pee: A national survey of urinary catheter users' costs and coverage.Journal of pediatric rehabilitation medicine · 2024Article
- Multidisciplinary management of people with spina bifida across the lifespan.Pediatric nephrology (Berlin, Germany) · 2024Review
- The urological evaluation and management of neurogenic bladder in children and adolescents-what every pediatric nephrologist needs to know.Pediatric nephrology (Berlin, Germany) · 2024Article
- 2023 Canadian Urological Association/Pediatric Urologists of Canada guideline: Pediatric patients with neurogenic lower urinary tract dysfunction Full-text version.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023Article
- What has changed in pediatric neurosurgical care in spina bifida? A 30-year UAB/Children's of Alabama observational overview.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Variation in Definitions of Kidney Abnormality in Patients with Spina Bifida: A Systematic Scoping Review.The Journal of urology · 2022Article
- Parents' report on the health care management of spina bifida in early childhood.Journal of pediatric rehabilitation medicine · 2022Article
- Incidence of Urinary Tract Infections in Newborns with Spina Bifida-Is Antibiotic Prophylaxis Necessary?The Journal of urology · 2021Article
- Diagnostic Test Characteristics of Ultrasound Based Hydronephrosis in Identifying Low Kidney Function in Young Patients with Spina Bifida: A Retrospective Cohort Study.The Journal of urology · 2021Article
- Projected impact of mandatory food fortification with folic acid on neurosurgical capacity needed for treating spina bifida in Ethiopia.Birth defects research · 2021Article
- Prioritization and management recommendations of pediatric urology conditions during the COVID-19 pandemic.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020Article
- Urologic guidelines for the care and management of people with spina bifida.Journal of pediatric rehabilitation medicineReview
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Authors and funding
14 authors.
Funding
Abstract
purposeThe lifetime risk of renal damage in children with spina bifida is high but only limited baseline imaging data are available for this population. We evaluated a large prospective cohort of infants with spina bifida to define their baseline imaging characteristics. MATERIALS AND
methodsThe UMPIRE Protocol for Young Children with Spina Bifida is an iterative quality improvement protocol that follows a cohort of newborns at 9 United States centers. Using descriptive statistics, we report the initial baseline imaging characteristics, specifically regarding renal bladder ultrasound, cystogram and dimercaptosuccinic acid nuclear medicine scan.
resultsData on 193 infants from 2015 to 2018 were analyzed. Renal-bladder ultrasound was normal in 55.9% of infants, while 40.4% had Society for Fetal Urology grade 1 to 2 hydronephrosis in at least 1 kidney, 3.7% had grade 3 to 4 hydronephrosis in either kidney and 21.8% had grade 1 or higher bilateral hydronephrosis. There was no vesicoureteral reflux in 84.6% of infants. A third of enrolled infants underwent dimercaptosuccinic acid nuclear medicine renal scan, of whom 92.4% had no renal defects and 93.9% had a difference in differential function of less than 15%.
conclusionsThe majority of infants born with spina bifida have normal baseline imaging characteristics and normal urinary tract anatomy at birth. This proactive protocol offers careful scheduled surveillance of the urinary tract with the goal of lifelong maintenance of normal renal function and healthy genitourinary development.
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