Evidence map›Paper›PMID 30730410›Full record

Observational studyThe Journal of urology2019

The Comprehensive Assessment of Self-Reported Urinary Symptoms: A New Tool for Research on Subtypes of Patients with Lower Urinary Tract Symptoms.

Kevin P Weinfurt, James W Griffith, Kathryn E Flynn, David Cella, Tamara Bavendam, Jonathan B Wiseman, Victor P Andreev, H Henry Lai, Alice B Liu, Ziya Kirkali and 3 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in The Journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04557748 (Symptoms of Lower Urinary Tract Dysfunction Research Network), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04557748 completednot on this mapstarted 2021, after this paper: background citation

Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Urinary Urgency Phenotyping Protocol

TypeobservationalSponsorArbor Research Collaborative for HealthRan2021 to 2025Enrolled1,030ConditionsLower Urinary Tract SymptomsArmsObservational, Observational Controls, Central Sensitization, Physical Activity and Sleep Tracker, Physical Activity and Sleep Tracker Controls
3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Trial
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  4. Review
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Prevention of Urinary Stones With Hydration (PUSH): Design and Rationale of a Clinical Trial.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Observational
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kevin P WeinfurtDuke University Medical Center , Durham , North Carolina.
James W GriffithDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University , Chicago , Illinois.
Kathryn E FlynnMedical College of Wisconsin , Milwaukee , Wisconsin.
David CellaDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University , Chicago , Illinois.
Tamara BavendamNational Institute of Diabetes and Digestive and Kidney Diseases , Bethesda , Maryland.
Jonathan B WisemanArbor Research Collaborative for Health , Ann Arbor , Michigan.
Victor P AndreevArbor Research Collaborative for Health , Ann Arbor , Michigan.
H Henry LaiWashington University School of Medicine , St. Louis , Missouri.
Alice B LiuUniversity of Washington , Seattle , Washington.
Ziya KirkaliNational Institute of Diabetes and Digestive and Kidney Diseases , Bethesda , Maryland.
Anne P CameronUniversity of Michigan , Ann Arbor , Michigan.
Catherine S BradleyDepartment of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa , Iowa City , Iowa.
LURN Study Group

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Continuation of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Data Coordinating CenterU24DK099879 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI GRAFF, JOHN JOSEPH · 2019 to 2025
$6.9M
Phenotype of urinary symptoms and relationships with genotype, sleep and obesityU01DK097779 · NIDDK · UNIVERSITY OF CHICAGO · PI GRIFFITH, JAMES WILLIAM, KENTON, KIMBERLY SUE · 2012 to 2025
$5.7M
Advancing the Measurement and Classification of Lower Urinary Tract DysfunctionU01DK097780 · NIDDK · DUKE UNIVERSITY · PI AMUNDSEN, CINDY, JELOVSEK, JOHN ERIC · 2012 to 2025
$5.3M
University of Iowa LURN Research SiteU01DK097772 · NIDDK · UNIVERSITY OF IOWA · PI BRADLEY, CATHERINE S, KREDER, KARL J · 2012 to 2025
$5.0M
Expansion of Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)U01DK099879 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI MERION, ROBERT M · 2013 to 2018
$4.6M
University of Washington LURN Research SiteU01DK100011 · NIDDK · UNIVERSITY OF WASHINGTON · PI YANG, CLAIRE C · 2013 to 2025
$4.5M
University of Michigan LURN Research SiteU01DK099932 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLEMENS, J. QUENTIN · 2013 to 2023
$4.4M
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Second Phase StudyU01DK100017 · NIDDK · WASHINGTON UNIVERSITY · PI LAI, HING HUNG HENRY · 2013 to 2025
$3.9M
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)Data CoordinatU01DK097776 · NIDDK · ARBOR RESEARCH COLLABORATIVE FOR HEALTH · PI MERION, ROBERT M · 2012 to 2016
$1.7M
Epigenomics in insulin resistance associated overactive bladderK23DK110417 · NIDDK · DUKE UNIVERSITY · PI SIDDIQUI, NAZEMA Y · 2017 to 2019
$567k
NCATS NIH HHS UL1 TR001422NIDDK NIH HHS K23 DK110417NIDDK NIH HHS U01 DK097772NIDDK NIH HHS U01 DK097776NIDDK NIH HHS U01 DK097779NIDDK NIH HHS U01 DK097780NIDDK NIH HHS U01 DK099879NIDDK NIH HHS U01 DK099932NIDDK NIH HHS U01 DK100011NIDDK NIH HHS U01 DK100017NIDDK NIH HHS U24 DK099879
6 · The paper itself

Abstract

purposeTo improve the potential for finding clinically important subtypes of patients with lower urinary tract symptoms we developed the CASUS (Comprehensive Assessment of Self-reported Urinary Symptoms). We used it to present data on the experiences of lower urinary tract symptoms in treatment seeking women and men from a prospective observational cohort. MATERIALS AND

methodsWe created an initial list of lower urinary tract symptoms that were confirmed in 22 qualitative interviews with providers, and 88 qualitative interviews with care seeking and noncare seeking women and men with lower urinary tract symptoms. Items from extant measures were adopted and revised, and new items were developed. All items were evaluated for understanding in 64 cognitive interviews. Items were administered to a prospective cohort of female and male patients with lower urinary tract symptoms who were seeking care. Analyses were done to describe item response distributions and correlations among item responses separately for women and men.

resultsA total of 444 males and 372 females provided responses to the CASUS. Several sets of items showed different relationships for women compared to men. In particular the associations between sensation related items and incontinence related items were generally positive among females but often negative among males.

conclusionsAfter using an intensive development process the CASUS addresses a wide range of lower urinary tract symptoms. It should help identify clinically important subtypes of patients. Further, item collection can provide the foundation for shorter measures for use in the clinic and as trial end points.

Indexed as

Diagnostic Self EvaluationSymptom AssessmentAdultFemaleHumansLower Urinary Tract SymptomsMaleMiddle AgedProspective Studieslower urinary tract symptomspatient acceptance of health carepatient reported outcome measuressurveys and questionnairesurinary bladder

Identifiers

PMID30730410
PMCPMC6573020

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.