Evidence map›Paper›PMID 30730023›Full record

ArticleMagma (New York, N.Y.)2019

A study of within-subject reliability of the brain's default-mode network.

Merel Charlotte Postema, Matteo De Marco, Elisa Colato, Annalena Venneri

Abstract read
In one paragraph

Article in Magma (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Merel Charlotte PostemaDepartment of Neuroscience, University of Sheffield, Royal Hallamshire Hospital, Beech Hill Road, N Floor, Room N133, Sheffield, S10 2RX, UK.
Matteo De MarcoDepartment of Neuroscience, University of Sheffield, Royal Hallamshire Hospital, Beech Hill Road, N Floor, Room N133, Sheffield, S10 2RX, UK. m.demarco@sheffield.ac.uk.ORCID http://orcid.org/0000-0002-9240-8067
Elisa ColatoDepartment of Neuroscience, University of Sheffield, Royal Hallamshire Hospital, Beech Hill Road, N Floor, Room N133, Sheffield, S10 2RX, UK.
Annalena VenneriDepartment of Neuroscience, University of Sheffield, Royal Hallamshire Hospital, Beech Hill Road, N Floor, Room N133, Sheffield, S10 2RX, UK.

Funding

Seventh Framework Programme 42/RF-2010-2321718
6 · The paper itself

Abstract

objectiveResting-state functional magnetic resonance imaging (fMRI) is promising for Alzheimer's disease (AD). This study aimed to examine short-term reliability of the default-mode network (DMN), one of the main haemodynamic patterns of the brain. MATERIALS AND

methodsUsing a 1.5 T Philips Achieva scanner, two consecutive resting-state fMRI runs were acquired on 69 healthy adults, 62 patients with mild cognitive impairment (MCI) due to AD, and 28 patients with AD dementia. The anterior and posterior DMN and, as control, the visual-processing network (VPN) were computed using two different methodologies: connectivity of predetermined seeds (theory-driven) and dual regression (data-driven). Divergence and convergence in network strength and topography were calculated with paired t tests, global correlation coefficients, voxel-based correlation maps, and indices of reliability.

resultsNo topographical differences were found in any of the networks. High correlations and reliability were found in the posterior DMN of healthy adults and MCI patients. Lower reliability was found in the anterior DMN and in the VPN, and in the posterior DMN of dementia patients. DISCUSSION: Strength and topography of the posterior DMN appear relatively stable and reliable over a short-term period of acquisition but with some degree of variability across clinical samples.

Indexed as

AgedAlzheimer DiseaseBrainBrain MappingDementiaFemaleHealthy VolunteersHemodynamicsHumansMagnetic Resonance ImagingMaleMiddle AgedNerve NetNeural PathwaysNeuropsychological TestsRegression AnalysisBrain imagingfMRIHemodynamicsReproducibility of results

Identifiers

PMID30730023
PMCPMC6525123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.