ArticleJournal of biomedical optics2019
Terahertz spectroscopy of gelatin-embedded human brain gliomas of different grades: a road toward intraoperative THz diagnosis.
Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Terahertz-based prognostic framework for glioma: from spectral features to patient-level prognostic assessment.npj biomedical innovations · 2026Article
- Rapid diagnosis of TERT promoter mutation using Terahertz absorption spectroscopy in glioblastoma.Scientific reports · 2025Article
- A new horizon for neuroscience: terahertz biotechnology in brain research.Neural regeneration research · 2025Article
- High-sensitivity THz-ATR imaging of cerebral ischemia in a rat model.Biomedical optics express · 2024Article
- Biomedical application of terahertz imaging technology: a narrative review.Quantitative imaging in medicine and surgery · 2023Review
- Review
- Terahertz imaging of human skin pathologies using laser feedback interferometry with quantum cascade lasers.Biomedical optics express · 2023Article
- Discovering Glioma Tissue through Its Biomarkers' Detection in Blood by Raman Spectroscopy and Machine Learning.Pharmaceutics · 2023Article
- Measurement of tissue optical properties in a wide spectral range: a review [Invited].Biomedical optics express · 2023Review
- Advances in terahertz technology for cancer detection applications.Optical and quantum electronics · 2023Review
- Molecular pathological recognition of freshly excised human glioma using terahertz ATR spectroscopy.Biomedical optics express · 2022Article
- Temperature dependent terahertz spectroscopy and imaging of orthotopic brain gliomas in mouse models.Biomedical optics express · 2022Article
- Single-Fiber Diffuse Reflectance Spectroscopy and Spatial Frequency Domain Imaging in Surgery Guidance: A Study on Optical Phantoms.Materials (Basel, Switzerland) · 2021Article
- Moisture adsorption by decellularized bovine pericardium collagen matrices studied by terahertz pulsed spectroscopy and solid immersion microscopy.Biomedical optics express · 2021Article
- Cellular effects of terahertz waves.Journal of biomedical optics · 2021Review
- Terahertz dielectric spectroscopy and solid immersion microscopy ofBiomedical optics express · 2021Article
- Terahertz radiation and the skin: a review.Journal of biomedical optics · 2021Review
- Malignant and benign thyroid nodule differentiation through the analysis of blood plasma with terahertz spectroscopy.Biomedical optics express · 2021Article
- In situ terahertz monitoring of an ice ball formation during tissue cryosurgery: a feasibility test.Journal of biomedical optics · 2021Article
- Terahertz dielectric spectroscopy of human brain gliomas and intact tissuesBiomedical optics express · 2021Article
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16 authors.
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Abstract
We applied terahertz (THz)-pulsed spectroscopy to study ex vivo the refractive index and absorption coefficient of human brain gliomas featuring different grades, as well as perifocal regions containing both intact and edematous tissues. Glioma samples from 26 patients were considered and analyzed according to further histological examination. In order to fix tissues for the THz measurements, we applied gelatin embedding, which allows for sustaining their THz response unaltered, as compared to that of the freshly excised tissues. We observed a statistical difference between the THz optical constants of intact tissues and gliomas of grades I to IV, while the response of edema was similar to that of tumor. The results of this paper justify a potential of THz technology in the intraoperative label-free diagnosis of human brain gliomas for ensuring the gross-total resection.
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