Evidence map›Paper›PMID 30729746›Full record

ArticlePM & R : the journal of injury, function, and rehabilitation2019

Pregnancy Outcomes in Women with Spinal Cord Injuries: A Population-Based Study.

Deborah A Crane, David R Doody, Melissa A Schiff, Beth A Mueller

Abstract readComparative Study
In one paragraph

Article in PM & R : the journal of injury, function, and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deborah A CraneDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA.
David R DoodyPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Melissa A SchiffDepartment of Epidemiology, University of Washington, Seattle, WA.
Beth A MuellerPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA.

Funding

Pregnancy Outcomes in Women with Disabilities: Exploratory ResearchR21HD073024 · NICHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MUELLER, BETH A · 2013 to 2014
$480k
NICHD NIH HHS #1R21HD073024-01A1NICHD NIH HHS R21 HD073024
6 · The paper itself

Abstract

backgroundPregnant women with congenital or acquired spinal cord injury face challenges due to compromised neurologic function and mobility, factors that may also affect fetal/infant health. Few studies have examined pregnancy course and longer-term outcomes in this population.

objectiveTo assess pregnancy outcomes among women with spinal cord injury, paralysis, or spina bifida using population-based data.

designRetrospective cohort study.

settingWashington state linked birth-hospital discharge records.

participantsAll women (N = 529) with spinal cord injury, paralysis, or spina bifida with singleton live birth deliveries 1987-2012, and a comparison group of women without disabilities (N = 5282).

methodsDiagnosis codes were screened to identify cases and a 10:1 random sample of comparison women. Relative risks (RRs) and 95% confidence intervals (CIs) were calculated overall and separately for each condition using multivariable regression. Subsequent hospitalizations or death were identified via linkage to hospital discharge/death records for 2 years after delivery. MAIN OUTCOME MEASUREMENTS: Pregnancy course (weight gain, gestational diabetes, preeclampsia, infection, venous thromboembolism), delivery/labor characteristics, infant characteristics (birthweight/size, gestational age), and longer-term outcomes (occurrence/reasons for maternal/infant rehospitalization, mortality).

resultsWomen with these spinal conditions had increased adjusted risks of prenatal urinary tract infection/pyelonephritis (RR 26.43, 95% CI 13.97-49.99), venous thromboembolism (RR 9.16, 95% CI 2.17-38.60), preterm rupture of membranes (RR 2.15, 95% CI 1.18-3.90), and cesarean delivery (RR 1.88, 95% CI 1.70-2.09). They had longer hospitalizations and increased rehospitalization (RR 1.54, 95% CI 1.28-1.87), including for postpartum depression (RR 8.15, 4.29-15.48) or injury (RR 13.05, 95% CI 6.60-25.81). Their infants were more often small for gestational age (RR 1.65, 95% CI 1.33-2.06), but had no increased risk of rehospitalization or death.

conclusionsWe observed no increased long-term morbidity among infants of women with these conditions. Possible increased maternal morbidities during the first postpartum years indicate areas for intervention. LEVEL OF EVIDENCE: III.

Indexed as

Pregnancy, High-RiskPregnancy OutcomeCesarean SectionCohort StudiesConfidence IntervalsDatabases, FactualFemaleFollow-Up StudiesHumansPostnatal CarePregnancyPrenatal CareReference ValuesRetrospective StudiesSpinal Cord InjuriesSpinal Dysraphism

Identifiers

PMID30729746
PMCPMC6675642

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.