Evidence map›Paper›PMID 30729711›Full record

ArticleActa ophthalmologica2019

Swept-source optical coherence tomography angiography reveals vascular changes in intermediate uveitis.

Meng Tian, Christoph Tappeiner, Martin S Zinkernagel, Sebastian Wolf, Marion R Munk

Abstract read
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In one paragraph

Article in Acta ophthalmologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. A systematic review of OCT and OCT angiography in retinal vasculitis.Journal of ophthalmic inflammation and infection · 2023
    Review
  7. Article
  8. Optical coherence tomography angiography in intermediate uveitis-related cystoid macular edema.Medical hypothesis, discovery & innovation ophthalmology journal · 2022
    Article
  9. Changes in Choroidal Vascularity Index (CVI) in Intermediate Uveitis.Translational vision science & technology · 2021
    Article
  10. Article
  11. Review
  12. Quantitative optical coherence tomography angiography: A review.Experimental biology and medicine (Maywood, N.J.) · 2020
    Review
  13. Optical coherence tomography angiography (OCTA) as a new diagnostic tool in uveitis.Journal of ophthalmic inflammation and infection · 2019
    Review
  14. Advances in imaging of uveitis.Therapeutic advances in ophthalmology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Meng TianDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Christoph TappeinerDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0001-6907-1112
Martin S ZinkernagelDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Sebastian WolfDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Marion R MunkDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-6227-2242
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate retinal and choroidal vascular changes in patients with intermediate uveitis with/without concomitant retinal vasculitis using wide field swept-source optical coherence tomography angiography (OCTA).

methodsIn this study consecutive patients with intermediate uveitis ± vasculitis and healthy age-matched controls were evaluated using central 3 × 3 mm OCTA scans and montage scans. Differences among the groups as well as the association between central changes assessed by 3 × 3 scans and wide field OCTA were evaluated.

results93 eyes of 58 patients with intermediate uveitis and 33 healthy age-matched controls were included. The presence of a cystoid macular oedema (CME) was associated with capillary non-and reduced perfusion of the superficial capillary plexus (SCP) (p = 0.03 and 0.02, respectively), and deep capillary plexus (DCP) (p = 0.02 and p ≤ 0.0001, respectively) of the 3 × 3 mm scans. The raw length, circularity and size of foveal avascular area (FAZ) significantly differed among the three groups. (p = 0.01, p = 0.045 and p = 0.004, respectively). Multivariable regression analysis revealed that the presence of epiretinal membranes (ERM) and CME rather than the disease entity contributed to the changes of FAZ size (R

conclusionAlthough patients with intermediate uveitis and vasculitis present with reduced central vessel density compared to healthy age-matched controls, these changes are presumably contributed to the presence of CME.

Indexed as

Visual AcuityCapillariesCross-Sectional StudiesDisease ProgressionFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleMiddle AgedProspective StudiesReproducibility of ResultsRetinal VesselsTomography, Optical CoherenceUveitis, Intermediatefoveal avascular zone parameterintermediate uveitisoptical coherence tomography angiography (OCTA)retinal vasculitisvessel density

Identifiers

PMID30729711
OpenAlexW2914322870

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.