ArticleCell proliferation2019
Mast cells participate in regulation of lung-gut axis during Staphylococcus aureus pneumonia.
Article in Cell proliferation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Cell Death and Infection: Implications for Host and Microbe.Advances in experimental medicine and biology · 2025Review
- Review
- Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts.Cell reports · 2023Article
- Exploring the Role ofToxins · 2022Review
- Human mast cells exhibit an individualized pattern of antimicrobial responses.Immunity, inflammation and disease · 2020Article
- Unraveling the Interconnection Patterns Across Lung Microbiome, Respiratory Diseases, and COVID-19.Frontiers in cellular and infection microbiology · 2020Review
- SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infection.Cell proliferation · 2020Article
- The Cross-Talk Between Gut Microbiota and Lungs in Common Lung Diseases.Frontiers in microbiology · 2020Review
- Effects of Natural Products on Bacterial Communication and Network-Quorum Sensing.BioMed research international · 2020Review
- scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation.Genome biology · 2019Article
- Mast cells participate in regulation of lung-gut axis during Staphylococcus aureus pneumonia.Cell proliferation · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesThe lung-gut axis is known to be involved in the pathogenesis of Staphylococcus aureus pneumonia. However, the underlying mechanisms remain unclear. We examined the role of pulmonary mast cells (MCs) in the regulation of the lung-gut axis during S. aureus pneumonia. MATERIALS AND
methodsWe created a mouse model of S. aureus pneumonia using MC-deficient mice (Kit
resultsAfter S. aureus challenge, the MC-deficient mice, compared with wild-type (WT) mice, displayed attenuated lung inflammation, decreased expression of CRAMP, higher bacterial lung load and disturbance of the intestinal microbiota. Adoptive transfer of BMMCs into the lung effectively reconstituted the host defence against S. aureus in Kit
conclusionsThis study provides evidence for the involvement of MCs in the regulation of the lung-gut axis during S. aureus pneumonia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.