Evidence map›Paper›PMID 30729479›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Animal Models for the Study of Bone-Derived Pain.

Austen L Thompson, Tally M Largent-Milnes, Todd W Vanderah

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Potential therapeutic treatments of cancer-induced bone pain.Current opinion in supportive and palliative care · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Austen L ThompsonDepartment of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA.
Tally M Largent-MilnesDepartment of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA.
Todd W VanderahDepartment of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA. vanderah@email.arizona.edu.

Funding

Cannabinoid CB2 Agonists for Treatment of Breast Cancer-Induced Bone PainR01CA142115 · NCI · UNIVERSITY OF ARIZONA · PI VANDERAH, TODD W · 2010 to 2021
$3.3M
Primary Afferent Transmission in the Trigeminal Dorsal HornF32DE022499 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI MILNES, TALLY MARIE · 2011 to 2014
$127k
NCI NIH HHS R01 CA142115NIDCR NIH HHS F32 DE022499
6 · The paper itself

Abstract

Bone pain is a prevalent issue in society today and also is one of the hardest types of pain to control. Pain originating in the bone can be caused by many different entities including metastatic and primary neoplasm, fracture, osteoarthritis as well as numerous other metabolic disorders. In this chapter we describe the methods and protocols that currently are accepted and validated for the study of bone pain in models of metastatic cancer, bicortical fracture and osteoarthritis. These animal models provide invaluable information as to the nature of bone pain and give rise to potential new targets for its treatment and management.

Indexed as

Disease Models, AnimalAnimalsBehavior, AnimalBone and BonesBone NeoplasmsCell Culture TechniquesCell Line, TumorFemaleFractures, BoneHumansIodoacetic AcidMaleMammary Neoplasms, AnimalMiceMice, Inbred BALB COsteoarthritisIodoacetic AcidBone painCancer painFractureMetastatic diseaseOsteoarthritis

Identifiers

PMID30729479
PMCPMC7008003

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.