ReviewCurrent psychiatry reports2019
Does Prenatal Maternal Distress Contribute to Sex Differences in Child Psychopathology?
Review in Current psychiatry reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Socioeconomic factors and sex effects of postpartum maternal depression on offspring internalizing symptoms: a systematic review and meta-analysis.BMC medicine · 2025Pooled it
- Prenatal stress and externalizing behaviors in childhood and adolescence: A systematic review and meta-analysis.Psychological bulletin · 2024Pooled it
- Sex-dimorphic reprogramming of fetal mouse brain development by maternal estradiol excess.Biology of sex differences · 2025Article
- Pinpointing the timing of prenatal stress associated with infant biobehavioral reactivity.Psychoneuroendocrinology · 2025Article
- Maternal prenatal social disadvantage and neonatal functional connectivity: Associations with psychopathology symptoms at age 12 months.Developmental psychology · 2024Article
- Maternal psychological distress and temperament traits in children from infancy to late childhood.JCPP advances · 2024Article
- Maternal Childhood Adversity and Infant Epigenetic Aging: Moderation by Restless Sleep During Pregnancy.Developmental psychobiology · 2024Article
- Maternal Prenatal Depressive Symptoms and Fetal Growth During the Critical Rapid Growth Stage.JAMA network open · 2023Article
- Increases in maternal depressive symptoms during pregnancy and infant cortisol reactivity: Mediation by placental corticotropin-releasing hormone.Development and psychopathology · 2023Article
- Prenatal stress and child externalizing behavior: effects of maternal perceived stress and cortisol are moderated by child sex.Child and adolescent psychiatry and mental health · 2023Article
- Intergenerational risk and resilience pathways from discrimination and acculturative stress to infant mental health.Development and psychopathology · 2023Article
- Postnatal maternal distress, infant subcortical brain macrostructure and emotional regulation.Psychiatry research. Neuroimaging · 2023Article
- Maternal prenatal depressive symptoms and toddler behavior: an umbilical cord blood epigenome-wide association study.Translational psychiatry · 2022Article
- Intergenerational Transmission of Effects of Women's Stressors During Pregnancy: Child Psychopathology and the Protective Role of Parenting.Frontiers in psychiatry · 2022Article
- Urinary cortisol is lower in pregnant women with higher pre-pregnancy BMI.Frontiers in endocrinology · 2022Article
- Unpredictable maternal sensory signals in caregiving behavior are associated with child effortful control.PloS one · 2022Article
- The Person's Care Requires a Sex and Gender Approach.Journal of clinical medicine · 2021Review
- Childhood Anxiety: Prenatal Maternal Stress and Parenting in the QF2011 Cohort.Child psychiatry and human development · 2021Article
- Maternal stress during pregnancy alters fetal cortico-cerebellar connectivity in utero and increases child sleep problems after birth.Scientific reports · 2021Article
- Using Precision Medicine with a Neurodevelopmental Perspective to Study Inflammation and Depression.Current psychiatry reports · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewPrenatal maternal psychological distress is an established risk factor for the development of psychopathology in offspring. The purpose of this review is to evaluate whether sex differences in fetal responses to maternal distress contribute to sex differences in subsequent psychopathology. RECENT
findingsMale and female fetuses respond differently to stress signals. We review recent evidence that demonstrates a sex-specific pattern of association between prenatal maternal distress and pathways associated with risk for psychopathology including offspring hypothalamic pituitary adrenocortical (HPA) axis regulation, brain development, and negative emotionality. Prenatal maternal distress exerts sex-specific consequences on the fetus. These differences may contribute to the well-established sex differences in psychopathology and in particular to greater female vulnerability to develop internalizing problems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.