Evidence map›Paper›PMID 30729328›Full record

ReviewCurrent psychiatry reports2019

Links Between Stress, Sleep, and Inflammation: Are there Sex Differences?

Emily A. Dolsen, Alexandra D Crosswell, Aric A Prather

Open access · greenAbstract readReview
In one paragraph

Review in Current psychiatry reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

  1. Pooled it
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  5. Oxytocin as regulator of stress and inflammation in aging.Neuroscience and biobehavioral reviews · 2026
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Emily A. DolsenUniversity of California, Berkeley, CA, USA.
Alexandra D CrosswellCenter for Health and Community, Department of Psychiatry, University of California, San Francisco, CA, USA.
Aric A PratherCenter for Health and Community, Department of Psychiatry, University of California, San Francisco, CA, USA. aric.prather@ucsf.edu.
University of California, San Francisco · USUniversity of California, Berkeley · US

Funding

Stress, diet quality, and biological aging across the lifespanR24AG048024 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EPEL, ELISSA S., MENDES, WENDY BERRY · 2014 to 2025
$6.2M
PREDOCTORAL TRAINING CONSORTIUM IN AFFECTIVE SCIENCET32MH020006 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI GROSS, JAMES J, JOHNSON, SHERI L · 1998 to 2018
$5.9M
Examining the reciprocal effects of racial discrimination and sleep on cardiovascular functioning: An experimental approachR01HL142051 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PRATHER, ARIC ANDREW · 2018 to 2022
$3.5M
Stress resilience and aging in Alzheimers disease and dementia caregiversK01AG057859 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CROSSWELL, ALEXANDRA DUPONT · 2018 to 2022
$652k
NHLBI NIH HHS R01 HL142051NIA NIH HHS K01 AG057859NIA NIH HHS R24 AG048024NIMH NIH HHS T32 MH020006
6 · The paper itself

Abstract

purpose of reviewInflammation has emerged as an important biological process in the development of many age-related diseases that occur at different frequencies in men and women. The aim of this review was to examine the current evidence linking stress and sleep with inflammation with a focus on sex differences. RECENT

findingsPsychosocial stress that occurs either acutely or chronically is associated with elevated levels of systemic inflammation. While not as robust, insufficient sleep, particularly sleep disturbances, appears to be associated with higher levels of inflammatory activity as well. In several contexts, associations of stress and insufficient sleep with inflammation appear stronger in women than in men. However, this should be interpreted with caution as few studies test for sex differences. Stress and poor sleep often predict elevations in systemic inflammation. While there is some evidence that these associations are stronger in women, findings are largely mixed and more systematic investigations of sex differences in future studies are warranted.

Indexed as

Sex CharacteristicsFemaleHumansInflammationMaleSleepSleep Initiation and Maintenance DisordersStress, PsychologicalImmune systemInflammationSexSleepStress

Identifiers

PMID30729328
PMCPMC6426453
OpenAlexW2912125994

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.