Evidence map›Paper›PMID 30729224›Full record

ArticleACS omega2019

Preparation and Evaluation of ZD2 Peptide

Zheng Han, Olga Sergeeva, Sarah Roelle, Han Cheng, Songqi Gao, Yajuan Li, Zhenghong Lee, Zheng-Rong Lu

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. PET Imaging of Hepatocellular Carcinoma Using ZD2-(Journal of hepatocellular carcinoma · 2023
    Article
  5. Article
  6. Article
  7. Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  8. Synthesis and assessment of ZD2-(American journal of nuclear medicine and molecular imaging · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zheng HanDepartment of Biomedical Engineering and Department of Radiology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Olga SergeevaDepartment of Biomedical Engineering and Department of Radiology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Sarah RoelleDepartment of Biomedical Engineering and Department of Radiology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Han ChengDepartment of Biomedical Engineering and Department of Radiology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Songqi GaoDepartment of Biomedical Engineering and Department of Radiology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Yajuan LiMolecular Theranostics, Cleveland, Ohio 44115, United States.
Zhenghong LeeDepartment of Biomedical Engineering and Department of Radiology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Zheng-Rong LuDepartment of Biomedical Engineering and Department of Radiology, Case Western Reserve University, Cleveland, Ohio 44106, United States.
Case Western Reserve University · USMolecular Theranostics (United States) · US

Funding

Biodegradable Macromolecular Blood Pool Contrast AgentsR01EB000489 · NIBIB · UNIVERSITY OF UTAH · PI LU, ZHENG-RONG · 2003 to 2014
$3.3M
Image-guided EMT inhibition for treating metastatic breast cancerR01CA194518 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI LU, ZHENG-RONG, SCHIEMANN, WILLIAM · 2015 to 2019
$2.4M
Targeted MRI contrast agents for differential diagnosis of prostate cancerR01CA211762 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI LU, ZHENG-RONG · 2017 to 2021
$2.1M
Commercialization of an MRI contrast agent for differential diagnosis of prostate cancer.R44CA199826 · NCI · MOLECULAR THERANOSTICS, LLC · PI LI, YAJUAN · 2017 to 2019
$2.1M
Imaging Liver Cancer ProliferationR01CA204373 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI LEE, ZHENGHONG, SAUNTHARARAJAH, YOGEN · 2016 to 2021
$1.8M
Commercialization of targeted MRI contrast agents for prostate cancer imaging.R43CA199826 · NCI · MOLECULAR THERANOSTICS, LLC · PI LI, YAJUAN · 2015 to 2015
$250k
NCI NIH HHS R01 CA194518NCI NIH HHS R01 CA204373NCI NIH HHS R01 CA211762NCI NIH HHS R43 CA199826NCI NIH HHS R44 CA199826NIBIB NIH HHS R01 EB000489
6 · The paper itself

Abstract

Positron emission tomography (PET) is a sensitive modality for cancer molecular imaging. We aim to develop a PET probe for sensitive detection and risk stratification of prostate cancer by targeting an abundant microenvironment oncoprotein, extradomain-B fibronectin (EDB-FN). The probe consists of a small ZD2 peptide specific to EDB-FN and a

Identifiers

PMID30729224
PMCPMC6356864
OpenAlexW2909657791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.