Evidence map›Paper›PMID 30729156›Full record

ArticleScience advances2019

Transcriptional regulation of microalgae for concurrent lipid overproduction and secretion.

Da-Wei Li, Srinivasan Balamurugan, Yu-Feng Yang, Jian-Wei Zheng, Dan Huang, Li-Gong Zou, Wei-Dong Yang, Jie-Sheng Liu, Yuanfang Guan, Hong-Ye Li

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 157 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Enhancing lipid production inFrontiers in microbiology · 2025
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  5. NgAP2a TargetsInternational journal of molecular sciences · 2024
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  11. Marine drugs · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Increased Lipids inInternational journal of molecular sciences · 2022
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Da-Wei LiKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-1452-0264
Srinivasan BalamuruganKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-5445-6076
Yu-Feng YangKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Jian-Wei ZhengKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Dan HuangKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Li-Gong ZouKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Wei-Dong YangKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Jie-Sheng LiuKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Yuanfang GuanDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, 48109, USA.
Hong-Ye LiKey Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.ORCID 0000-0001-7427-0706
Jinan University · CNUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Commercialization of algal lipids and biofuels is still impractical owing to the unavailability of lipogenic strains and lack of economically viable oil extraction strategies. Because lipogenesis is governed by multiple factors, success in generating industrial-suitable algal strains using conventional strategies has been limited. We report the discovery of a novel bZIP1 transcription factor, NobZIP1, whose overexpression results in a remarkable elevation of lipid accumulation and lipid secretion in a model microalga

Indexed as

Transcription, GeneticBasic-Leucine Zipper Transcription FactorsBiofuelsCarbohydrate MetabolismCell WallChromatin ImmunoprecipitationFatty AcidsGene SilencingLipid MetabolismLipogenesisMicroalgaeStramenopilesSugar Alcohol DehydrogenasesBasic-Leucine Zipper Transcription FactorsBiofuelsFatty Acidsgalactitol 2-dehydrogenaseSugar Alcohol Dehydrogenases

Identifiers

PMID30729156
PMCPMC6353619
OpenAlexW2914197015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.