Evidence map›Paper›PMID 30729125›Full record

ArticleBioMed research international2019

Kisspeptin Protein in Seminal Plasma Is Positively Associated with Semen Quality: Results from the MARHCS Study in Chongqing, China.

Peng Zou, Xiaogang Wang, Qing Chen, Huan Yang, Niya Zhou, Lei Sun, Hongqiang Chen, Jinyi Liu, Lin Ao, Zhihong Cui and 1 more

Abstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Association of Kisspeptin and KISSReproductive sciences (Thousand Oaks, Calif.) · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. CRISPR/Cas9-editing ofFrontiers in genetics · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Kisspeptin and Testicular Function-Is it Necessary?International journal of molecular sciences · 2020
    Review
  15. Review
  16. Reproductive functions of Kisspeptin/KISS1R Systems in the Periphery.Reproductive biology and endocrinology : RB&E · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peng ZouKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.ORCID 0000-0001-9255-6986
Xiaogang WangKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Qing ChenKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Huan YangKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.ORCID 0000-0003-4570-2228
Niya ZhouKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Lei SunKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Hongqiang ChenKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Jinyi LiuKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Lin AoKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.
Zhihong CuiCollege of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.ORCID 0000-0001-9729-5375
Jia CaoKey Lab of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Institute of Toxicology, College of Preventive Medicine, Third Military Medical University, Chongqing 400038, China.ORCID 0000-0001-7209-2993

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the associations between kisspeptin levels in seminal plasma and blood plasma and semen quality. MATERIALS AND

methodsWe conducted a male reproductive health survey in June 2014. A total of 666 volunteers were recruited from colleges in Chongqing, China. All volunteers completed a questionnaire including information on domestic characteristics and some potential confounders. We tested the kisspeptin levels in both blood and seminal plasma. Total seminal kisspeptin was calculated as the concentration of kisspeptin in seminal plasma multiplied by semen volume. Semen samples were tested according to the 2010 World Health Organization's (WHO) guidelines. Spearman correlation and multivariate linear regression were used to explore the association between kisspeptin concentrations in seminal plasma and blood plasma and semen quality. Potential confounders that were adjusted for included age, abstinence time, body mass index (BMI), grade, and smoking.

resultsThe median of kisspeptin levels in seminal plasma was 60,000 times higher than kisspeptin in blood plasma (28.0 × 10

conclusionThe positive association between kisspeptin levels in seminal plasma and semen quality supported an important role for the

Indexed as

AdultBody Mass IndexChinaHumansInfertility, MaleKisspeptinsMaleReceptors, Kisspeptin-1ReproductionSemenSemen AnalysisSperm CountSperm MotilityKISS1 protein, humanKISS1R protein, humanKisspeptinsReceptors, Kisspeptin-1

Identifiers

PMID30729125
PMCPMC6343164

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.