Evidence map›Paper›PMID 30728930›Full record

ArticleTherapeutic advances in chronic disease2019

Comparing iStent versus CyPass with or without phacoemulsification in patients with glaucoma: a meta-analysis.

Ali Mahdavi Fard, Sangita P Patel, Leili Pourafkari, Nader D Nader

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in chronic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Ali Mahdavi FardDepartment of Ophthalmology, University at Buffalo, Buffalo, NY, USA Tabriz University of Medical Sciences, Tabriz, Iran.
Sangita P PatelDepartment of Ophthalmology, Ross Eye Institute, The State University of New York at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, USA Ophthalmology and Research Service, Veterans Administration Western New York Healthcare, System, Buffalo, NY, USA SUNY Eye Institute, Buffalo, NY, USA.
Leili PourafkariUniversity at Buffalo, Buffalo, NY, USA.
Nader D NaderDepartment of Anesthesiology, University at Buffalo, 77 Goodell Street, Suite #550, Buffalo, NY 14203, USA.ORCID https://orcid.org/0000-0002-5744-7319
University at Buffalo, State University of New York · USTabriz University of Medical Sciences · IRVA Western New York Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

bacgroundThe aim of this study was to conduct a meta-analysis to compare the overall intraocular pressure (IOP)-lowering effect of iStent or CyPass as isolated procedures or in combination with cataract extraction. MATERIALS AND

methodsCochrane review manager 5.3 software (RevMan MAIN

resultsA total of 33 out of 446 publications retrieved have been enrolled. The mean changes in IOP in the groups with one iStent and more than two iStents with concurrent cataract extraction were -3.78 ± 0.53 mmHg and -3.89 ± 0.73 mmHg, respectively. The mean differences in IOP in the groups with one iStent and more than two iStents without concurrent cataract extraction were -3.96 ± 0.25 mmHg and -7.48 ± 0.55 mmHg, respectively. The mean changes in IOP in the groups with CyPass implantation with and without concurrent cataract extraction were -4.97 ± 1.38 mmHg and -8.96 ± 0.16 mmHg, respectively.

conclusionsBoth iStent and CyPass either in combination with cataract extraction or as isolated procedures effectively decrease IOP. This effect is greatest with isolated implantation of CyPass followed by multiple iStents and then single iStent implantation and lasts up to 2 years.

Indexed as

cataracteye surgeryglaucomaintraocular pressure

Identifiers

PMID30728930
PMCPMC6357298
OpenAlexW2911699086

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.