Evidence map›Paper›PMID 30728904›Full record

ArticleOncotarget2019

Sustained response of three pediatric BRAF

Stephanie A Toll, Hung N Tran, Jennifer Cotter, Alexander R Judkins, Benita Tamrazi, Jaclyn A Biegel, Girish Dhall, Nathan J Robison, Kaaren Waters, Palak Patel and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
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  11. Case report:Frontiers in medicine · 2022
    Article
  12. Resistance mechanisms in BRAFFrontiers in oncology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Stephanie A Toll *Division of Hematology, Oncology and Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Hung N Tran *Kaiser Permanente Southern California, Los Angeles, CA, USA.
Jennifer CotterUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Alexander R JudkinsUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Benita TamraziUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Jaclyn A BiegelUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Girish DhallDivision of Hematology, Oncology and Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Nathan J RobisonDivision of Hematology, Oncology and Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Kaaren WatersDivision of Hematology, Oncology and Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Palak PatelUniversity of Southern California Keck School of Medicine, Los Angeles, CA, USA.
Robert Cooper *Kaiser Permanente Southern California, Los Angeles, CA, USA.
Ashley S Margol *Division of Hematology, Oncology and Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA, USA.
University of Southern California · USChildren's Center · USChildren's Hospital of Los Angeles · USKaiser Permanente · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outcomes for children with high-grade gliomas (HGG) remain dismal despite aggressive treatment strategies. The use of targeted therapy for BRAF

Indexed as

BRAF mutationhigh-grade gliomapediatricstargeted therapy

Identifiers

PMID30728904
PMCPMC6355184
OpenAlexW2908805720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.