Evidence map›Paper›PMID 30728888›Full record

ArticleOxidative medicine and cellular longevity2019

Hypoxia-Activated PI3K/Akt Inhibits Oxidative Stress via the Regulation of Reactive Oxygen Species in Human Dental Pulp Cells.

Fei Liu, Xin Huang, Zhenhua Luo, Jingjun He, Farhan Haider, Ci Song, Ling Peng, Ting Chen, Buling Wu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

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  16. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Fei LiuDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0001-7699-0977
Xin HuangDepartment of Stomatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.
Zhenhua LuoDivision of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
Jingjun HeInternational Medical Center, Guangdong Second Provincial General Hospital, Guangzhou 510317, China.
Farhan HaiderDepartment of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0001-6736-099X
Ci SongDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Ling PengDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0003-2465-9056
Ting ChenDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0001-8648-7136
Buling WuDepartment of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0002-9678-6962
Nanfang Hospital · CNCincinnati Children's Hospital Medical Center · USGuangzhou Medical University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to use stem cells as a resource for tissue regeneration, it is necessary to induce expansion

Indexed as

AdolescentAdultDental PulpHumansOxidative StressPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSignal TransductionStem CellsYoung AdultPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen Species

Identifiers

PMID30728888
PMCPMC6343138
OpenAlexW2910818467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.