Evidence map›Paper›PMID 30728850›Full record

ArticleComputational and mathematical methods in medicine2018

Oscillatory Patterns of Phase Cone Formations near to Epileptic Spikes Derived from 256-Channel Scalp EEG Data.

Ceon Ramon, Mark D Holmes, Mackenzie V Wise, Don Tucker, Kevin Jenson, Samuel R Kinn

Open access · hybridAbstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ceon RamonDepartment of Electrical and Computer Engineering, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0001-8675-613X
Mark D HolmesRegional Epilepsy Center, Department of Neurology, University of Washington, Seattle, WA 98195, USA.
Mackenzie V WiseRegional Epilepsy Center, Department of Neurology, University of Washington, Seattle, WA 98195, USA.
Don TuckerDepartment of Psychology, University of Oregon, Eugene, OR 97403, USA.
Kevin JensonRegional Epilepsy Center, Department of Neurology, University of Washington, Seattle, WA 98195, USA.
Samuel R KinnDepartment of Electrical and Computer Engineering, University of Washington, Seattle, WA 98195, USA.
University of Washington · USUniversity of Oregon · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective was to determine if there are any distinguishable phase cone clustering patterns present near to epileptic spikes. These phase cones arise from episodic phase shifts due to the coordinated activity of cortical neurons at or near to state transitions and can be extracted from the high-density scalp EEG recordings. The phase cone clustering activities in the low gamma band (30-50 Hz) and in the ripple band (80-150 Hz) were extracted from the analytic phase after taking Hilbert transform of the 256-channel high density (dEEG) data of adult patients. We used three subjects in this study. Spatiotemporal contour plots of the unwrapped analytic phase with 1.0 ms intervals were constructed using a montage layout of 256 electrode positions. Stable phase cone patterns were selected based on the criteria that the sign of the spatial gradient did not change for at least three consecutive time samples and the frame velocity was within the range of propagation velocities of cortical axons. These plots exhibited dynamical formation of phase cones which were higher in the seizure area as compared with the nearby surrounding brain areas. Spatiotemporal oscillatory patterns were also visible during ±5 sec period from the location of the spike. These results suggest that the phase cone activity might be useful for noninvasive localization of epileptic sites and also for examining the cortical neurodynamics near to epileptic spikes.

Indexed as

Action PotentialsAdultBrain MappingCluster AnalysisData Interpretation, StatisticalDiagnosis, Computer-AssistedElectrodesElectroencephalographyEpilepsyFemaleGamma RhythmHumansMaleScalpSeizuresSignal Processing, Computer-Assisted

Identifiers

PMID30728850
PMCPMC6343174
OpenAlexW2900508046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.