Evidence map›Paper›PMID 30728846›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Estrogenic Effect of the Extract of QingYan Formula on Reproductive Tissues in Immature Mice.

Yuan Zhao, Hong-Xia Zheng, Ying Xu, Na Lin

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Treatment of Cesarean Scar Pregnancy with Traditional Chinese Medicine and Warming Moxibustion.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yuan ZhaoTianjin University of Traditional Chinese Medicine, Tianjin, China.
Hong-Xia ZhengInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Ying XuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0002-4516-5314
Na LinInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0002-4221-7617
Chinese Academy of Medical Sciences & Peking Union Medical College · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A Chinese herbal preparation, QingYan formula (QYF), has been used clinically for kidney-invigorating. However, no evidence base links QYF to estrogen replacement therapy. In this study, the estrogenic effects of QingYan formula 70% ethanol extract (QYFE) were investigated in immature mice. Immature mice were treated with QYFE at doses of 1, 2, and 4g/kg for 7 days. QYFE treatments promoted vaginal cornification and prolonged the estrus status of the immature mice, promoted the growth and development of uterus and vagina, upregulated ER

Identifiers

PMID30728846
PMCPMC6341256
OpenAlexW2908824414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.