ArticleFrontiers in neurology2019
Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries.
Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Brain-Computer Interfaces for Children With Complex Communication Needs and Limited Mobility: A Systematic Review.Frontiers in human neuroscience · 2021Pooled it
- Eye-Tracking Technologies for Cognitive Assessment After Acquired Brain Injury: Systematic Review.JMIR rehabilitation and assistive technologies · 2026Review
- Human brain local field potential recordings during a battery of multilingual cognitive and eye-tracking tasks.Scientific data · 2025Article
- Eye tracking to support assessment of patients with prolonged disorder of consciousness - a case series.Journal of rehabilitation medicine · 2025Observational
- Article
- Application of High-Tech Solution for Memory Assessment in Patients With Disorders of Consciousness.Frontiers in neurology · 2022Article
- Development of a Sensing Platform Based on Hands-Free Interfaces for Controlling Electronic Devices.Frontiers in human neuroscience · 2022Article
- CyberEye: New Eye-Tracking Interfaces for Assessment and Modulation of Cognitive Functions beyond the Brain.Sensors (Basel, Switzerland) · 2021Article
- Methodological aspects of using a wearable eye-tracker to support diagnostic clinical evaluation of prolonged disorders of consciousness.Journal of rehabilitation medicine · 2021Observational
- Effect of Retinohypothalamic Tract Dysfunction on Melatonin Level in Patients with Chronic Disorders of Consciousness.Brain sciences · 2021Article
- Brain-Computer Interfaces in Neurorecovery and Neurorehabilitation.Seminars in neurology · 2021Article
- Post-comatose patients with minimal consciousness tend to preserve reading comprehension skills but neglect syntax and spelling.Scientific reports · 2019Article
- Visual Behavior, Pupil Dilation, and Ability to Identify Emotions From Facial Expressions After Stroke.Frontiers in neurology · 2019Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the first clinical signs differentiating the minimally conscious state from the vegetative state is the presence of smooth pursuit eye movements occurring in direct response to moving salient stimuli. Glasgow Coma Scale (GCS) is one of the most commonly used diagnostic tools for acute phase assessment of the level of consciousness, together with a neurological examination. These classic measures are limited to qualitative neurological examination without more quantitative measures provided from e.g., tasks with tracking position of the gaze. Among this and other limitations, it is prone to a relatively high rate of misdiagnosis. Here, we developed an interface for gaze tracking to enhance the assessment of consciousness in 10 patients with acquired brain injuries. According to the acute phase GCS assessment, nine of them were considered unaware and below the minimally conscious state. Chronic neurological examination confirmed six of them below the minimally conscious state. Our new Human Computer Interface (HCI) revealed that six patients were conscious enough to complete at least one of the gaze tracking tasks. Among these six patients, one was originally diagnosed as remaining in a vegetative state and one in coma. The patient diagnosed as remaining in a chronic vegetative state scored six GCS points acutely. Following assessment with our HCI the patient was re-diagnosed with a possible locked-in syndrome. Our HCI method provides a new complementary tool for clinical assessment of patients suffering from disorders of consciousness.
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