Evidence map›Paper›PMID 30728765›Full record

ArticleFrontiers in neuroscience2019

Revisiting the Sequence Method for Baroreflex Analysis.

Luiz Eduardo Virgilio Silva, Daniel Penteado Martins Dias, Carlos Alberto Aguiar da Silva, Hélio Cesar Salgado, Rubens Fazan

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  3. Effects of exercise training on autonomic modulation and mood symptoms in patients with obstructive sleep apnea.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2021
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  4. Article
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  7. Relationship between resting augmentation index and spontaneous cardiac baroreflex sensitivity during handgrip exercise in postmenopausal women.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
  8. Article
  9. On the accuracy of sequence methods for baroreflex sensitivity estimation.Physical and engineering sciences in medicine · 2024
    Article
  10. Article
  11. Impairment on Cardiovascular Autonomic Modulation in Women with Migraine.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luiz Eduardo Virgilio SilvaDepartment of Physiology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Daniel Penteado Martins DiasBarão de Mauá University Center, Ribeirão Preto, Brazil.
Carlos Alberto Aguiar da SilvaDepartment of Physiology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Hélio Cesar SalgadoDepartment of Physiology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Rubens FazanDepartment of Physiology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sequence method is an important approach to assess the baroreflex function, mainly because it is based on the spontaneous fluctuations of beat-by-beat arterial pressure (for example, systolic arterial pressure or SAP) and pulse interval (PI). However, some studies revealed that the baroreflex effectiveness index (BEI), calculated through the sequence method, shows an intriguing oscillatory pattern as function of the delay between SAP and PI. It has been hypothesized that this pattern is related to the respiratory influence on SAP and/or PI variability, limiting the SAP ramps to 3 or 4 beats of length. In this study, this hypothesis was tested by assessing the sequence method using raw (original) and filtered series. Results were contrasted to the well-established transfer function, estimated between SAP and PI. Continuous arterial pressure recordings were obtained from healthy rats (

Indexed as

autonomic nervous systembaroreflexeffectiveness indexheart rate variabilitysensitivitysequence method

Identifiers

PMID30728765
PMCPMC6352748

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.