Evidence map›Paper›PMID 30728537›Full record

ReviewNature medicine2019

Precision epidemiology for infectious disease control.

Jason T Ladner, Nathan D Grubaugh, Oliver G Pybus, Kristian G Andersen

Abstract readReview
In one paragraph

Review in Nature medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Inferring Sexual Network Bridging Using Genomics: A Simulation Study.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Review
  5. Article
  6. Cross-species transmission ofFrontiers in cellular and infection microbiology · 2026
    Review
  7. Observational
  8. Article
  9. Article
  10. Real-time, multi-pathogen wastewater genomic surveillance with Freyja 2.medRxiv : the preprint server for health sciences · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Genomic epidemiology of West Nile virus in Europe.One health (Amsterdam, Netherlands) · 2024
    Review
  17. Article
  18. Review
  19. Review
  20. Coupled models of genomic surveillance and evolving pandemics with applications for timely public health interventions.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jason T LadnerPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ, USA.
Nathan D GrubaughDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Oliver G PybusDepartment of Zoology, University of Oxford, Oxford, UK.
Kristian G AndersenDepartment of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. andersen@scripps.edu.ORCID http://orcid.org/0000-0001-6431-5982

Funding

Technology CoreU19AI135995 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI DOUGLAS A LAUFFENBURGER · 2018 to 2026
$32.0M
Scripps Translational Science InstituteUL1TR001114 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2013 to 2017
$24.0M
Analysis of Zika virus emergence and functional evolution in the AmericasR21AI137690 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI ANDERSEN, KRISTIAN GRAUGAARD · 2018 to 2019
$547k
NCATS NIH HHS UL1 TR001114NIAID NIH HHS HHSN272201400048CNIAID NIH HHS R21 AI137690NIAID NIH HHS U19 AI135995
6 · The paper itself

Abstract

Advances in genomics and computing are transforming the capacity for the characterization of biological systems, and researchers are now poised for a precision-focused transformation in the way they prepare for, and respond to, infectious diseases. This includes the use of genome-based approaches to inform molecular diagnosis and individual-level treatment regimens. In addition, advances in the speed and granularity of pathogen genome generation have improved the capability to track and understand pathogen transmission, leading to potential improvements in the design and implementation of population-level public health interventions. In this Perspective, we outline several trends that are driving the development of precision epidemiology of infectious disease and their implications for scientists' ability to respond to outbreaks.

Indexed as

Communicable Disease ControlCommunicable DiseasesDisease OutbreaksGenomicsHumans

Identifiers

PMID30728537
PMCPMC7095960

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.