ArticleScientific reports2019
Arabidopsis HUA ENHANCER 4 delays flowering by upregulating the MADS-box repressor genes FLC and MAF4.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 31 citations in OpenAlex.
- Does a chloroplast membrane protein bind DNA in the nucleus?Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The chromatin reader MBD4 regulates temperature- and flowering-responsive transcription by recognizing histone arginine methylation.Plant communications · 2026Article
- Article
- The KH-domain genes FLK and HOS5 integrate flowering and stress responses in Arabidopsis thaliana.Journal of experimental botany · 2025Article
- Integrated expression analysis to elucidate the role of miR394 during flowering in Arabidopsis thaliana.Plant cell reports · 2025Article
- Article
- Genomics of ecological adaptation in Canary IslandEcology and evolution · 2024Article
- Identification and Functional Analysis ofInternational journal of molecular sciences · 2024Article
- Exploring the Regulatory Dynamics ofInternational journal of molecular sciences · 2024Article
- Comparative transcriptomic analysis of male and females in the dioecious weeds Amaranthus palmeri and Amaranthus tuberculatus.BMC plant biology · 2023Article
- The flowering time regulator FLK controls pathogen defense in Arabidopsis thaliana.Plant physiology · 2023Article
- Chlorate-induced molecular floral transition revealed by transcriptomes.Open life sciences · 2023Article
- Valsa mali secretes an effector protein VmEP1 to target a K homology domain-containing protein for virulence in apple.Molecular plant pathology · 2022Article
- Genome-Wide Characterization and Expression Analysis of KH Family Genes Response to ABA and SA inInternational journal of molecular sciences · 2022Article
- Beyond the Genetic Pathways, Flowering Regulation Complexity inInternational journal of molecular sciences · 2021Review
- Identification and characterization of MADS box gene family in pigeonpea for their role during floral transition.3 Biotech · 2021Article
- The Arabidopsis KH-domain protein FLOWERING LOCUS Y delays flowering by upregulating FLOWERING LOCUS C family members.Plant cell reports · 2020Article
- Copper deficiency alters shoot architecture and reduces fertility of both gynoecium and androecium inPlant direct · 2020Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The adaptive success of flowering plants is largely due to their ability to align floral production with optimal conditions. In Arabidopsis thaliana, MADS-box repressors of the FLC/MAF-clade prevent flowering under non-inductive conditions, although the role of some members is not yet clearly defined. Using a genetic strategy, we identified the KH-domain gene HEN4, previously shown to be involved in MADS-box floral homeotic gene regulation, as a modulator of flowering time. Loss-of-function hen4 mutants are early-flowering, and their response to low growth-temperature (16 °C) and day-length is altered. Interestingly, hen4 plants showed dramatic reduction of FLC and MAF4 transcripts, whereas other flowering repressors of the same clade (FLM, MAF2, MAF3, MAF5) remained unaltered. We also determined that hen4, partly due to loss of FLC, accelerates the vegetative phase-change. This report provides insight into flowering time control and highlights the potential of versatile regulators such as HEN4 to coordinate the juvenile-to-adult transition and floral timing.
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