ArticleScientific reports2019
Paternal leakage and mtDNA heteroplasmy in Rhipicephalus spp. ticks.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Sperm mitochondrial DNA copy number: a marker of male fertility and reproductive success.Human reproduction update · 2026Review
- Evidence for Paternal Mitochondrial DNA Leakage in Diploid Hybrid Fish Lineages.Animals : an open access journal from MDPI · 2026Article
- Pervasive non-random mitochondrial DNA heteroplasmy in the hybrid water frog Pelophylax esculentus.BMC ecology and evolution · 2025Article
- Multiple Introductions of the Asian Longhorned Tick (Ecology and evolution · 2025Article
- Article
- The Rhipicephalus sanguineus group: updated list of species, geographical distribution, and vector competence.Parasites & vectors · 2024Review
- Pervasive heteroplasmy in an invasive ambrosia beetle (Scolytinae) in southern California.Heredity · 2024Article
- Characterization and trans-generation dynamics of mitogene pool in the silver carp (Hypophthalmichthys molitrix).G3 (Bethesda, Md.) · 2024Article
- Article
- Evidence for hybridization-driven heteroplasmy maintained across generations in a ricefish endemic to a Wallacean ancient lake.Biology letters · 2024Article
- Article
- Genetic Variation inInternational journal of environmental research and public health · 2022Article
- Unparalleled mitochondrial heteroplasmy andCurrent research in insect science · 2022Article
- Selection for biparental inheritance of mitochondria under hybridization and mitonuclear fitness interactions.Proceedings. Biological sciences · 2021Article
- mtDNA Heteroplasmy: Origin, Detection, Significance, and Evolutionary Consequences.Life (Basel, Switzerland) · 2021Review
- Comparative hologenomics of twoPeerJ · 2021Article
- Distant hybrids of Heliocidaris crassispina (♀) and Strongylocentrotus intermedius (♂): identification and mtDNA heteroplasmy analysis.BMC evolutionary biology · 2020Article
- Article
- Intracellular quality control of mitochondrial DNA: evidence and limitations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Ancient hybridization and mtDNA introgression behind current paternal leakage and heteroplasmy in hybrid zones.Scientific reports · 2019Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paternal leakage of mitochondrial DNA (mtDNA) and heteroplasmy have been recently described in several animal species. In arthropods, by searching in the Scopus database, we found only 23 documented cases of paternal leakage. Therefore, although arthropods represent a large fraction of animal biodiversity, this phenomenon has been investigated only in a paucity of species in this phylum, thus preventing a reliable estimate of its frequency. Here, we investigated the occurrence of paternal leakage and mtDNA heteroplasmy in ticks belonging to one of the most significant tick species complexes, the so-called Rhipicephalus sanguineus sensu lato. By developing a multiplex allele-specific PCR assay targeting a fragment of the 12S rRNA ribosomal region of the mtDNA, we showed the occurrence of paternal leakage and mtDNA heteroplasmy in R. sanguineus s.l. ticks originated from experimental crosses, as well as in individuals collected from the field. Our results add a new evidence of paternal leakage in arthropods and document for the first time this phenomenon in ticks. Furthermore, they suggest the importance of using allele-specific assays when searching for paternal leakage and/or heteroplasmy, as standard sequencing methods may fail to detect the rare mtDNA molecules.
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