ArticleScience translational medicine2019
Recurrent group A
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Article in Science translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
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91citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
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Who cites it
91 citing papers in PubMed, 119 citations in OpenAlex.
- Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation.Health technology assessment (Winchester, England) · 2023Trial
- CD9Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Association of Adult Chronic Rhinosinusitis With Pediatric Tonsillectomy and Adenoidectomy.The Laryngoscope · 2026Article
- SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children.Nature communications · 2026Article
- Multivalent nanobodies for potent and broad neutralization of Staphylococcus aureus toxins.Nature communications · 2026Article
- Rational selection of antigenic targets for Group A Streptococcus vaccine: updates, challenges and opportunities.NPJ vaccines · 2026Review
- Acquisition of toxin-encoding lysogenic bacteriophage elements enhances the virulence of pandemicInfection and immunity · 2026Article
- Divergent phenotypic and functional roles of human T follicular helper cells from infancy to adulthood.bioRxiv : the preprint server for biology · 2026Article
- T cells in Group AFrontiers in cellular and infection microbiology · 2026Review
- Tfh2 and a subset of Tfh1 cells associate with antibody-mediated immunity to malaria.JCI insight · 2025Article
- SARS-CoV-2 infection and vaccination elicit distinct pharyngeal mucosal B cell responses in children.Research square · 2025Article
- KMT2D coordinates antiviral CD4Cell reports · 2025Article
- Proinflammatory synergy between protease and superantigen streptococcal pyogenic exotoxins.Infection and immunity · 2025Article
- Microbial Composition, Antibiotic Sensitivity Patterns, and Contributing Factors Among Children With Tonsillitis in Hawassa Town, Sidama, Ethiopia.International journal of microbiology · 2025Article
- Identification of circulating Tfh/Th subsets as a biomarker of developed hospital-acquired pneumonia.Frontiers in immunology · 2025Article
- Comparison of Group A Streptococcus Antigen Detection and Pathogen Culture in Paediatric Infections.Infection and drug resistance · 2025Article
- A mini review of the pathogenesis of acute rheumatic fever and rheumatic heart disease.Frontiers in cellular and infection microbiology · 2025Review
- The intricate pathogenicity of Group AVirulence · 2024Review
- Dopamine receptor autoantibody signaling in infectious sequelae differentiates movement versus neuropsychiatric disorders.JCI insight · 2024Article
- Enhanced Staphylococcus aureus protection by uncoupling of the α-toxin-ADAM10 interaction during murine neonatal vaccination.Nature communications · 2024Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
19 authors at 6 institutions in 2 countries.
Jennifer M DanDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.ORCID 0000-0002-1672-0657
Colin Havenar-DaughtonDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.ORCID 0000-0002-2880-3927
Kayla KendricDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Rita Al-KollaDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Kirti KaushikDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Sandy L RosalesDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Ericka L AndersonDepartment of Pediatrics, School of Medicine, UCSD, La Jolla, CA 92037, USA.
Christopher N LaRockDepartment of Pediatrics, School of Medicine, UCSD, La Jolla, CA 92037, USA.ORCID 0000-0003-3035-5331
Pandurangan VijayanandDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.ORCID 0000-0001-7067-9723
Grégory SeumoisDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.ORCID 0000-0002-8164-6852
David LayfieldCancer Sciences Division, Faculty of Medicine, University of Southampton, UK.
Ramsey I CutressCancer Sciences Division, Faculty of Medicine, University of Southampton, UK.
Christian H OttensmeierCancer Sciences Division, Faculty of Medicine, University of Southampton, UK.ORCID 0000-0003-3619-1657
Cecilia S Lindestam ArlehamnDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.ORCID 0000-0001-7302-8002
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.ORCID 0000-0001-7013-2250
Victor NizetDepartment of Pediatrics, School of Medicine, UCSD, La Jolla, CA 92037, USA.ORCID 0000-0003-3847-0422
Marcella BothwellDivision of Pediatric Otolaryngology, Rady Children's Hospital, San Diego, CA 92123, USA.ORCID 0000-0001-9771-6221
Matthew BriggerDivision of Pediatric Otolaryngology, Rady Children's Hospital, San Diego, CA 92123, USA.ORCID 0000-0002-3528-1696
Shane CrottyDivision of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA. shane@lji.org.ORCID 0000-0002-6484-6262
La Jolla Institute for Immunology · USUniversity of Southampton · GBInternational AIDS Vaccine Initiative · USNaval Medical Center San Diego · USUniversity of California San Diego · USEmory Healthcare · US
Funding
Support Component D/Vaccine Discovery, Concept to ClinicUM1AI100663 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BAROUCH, DAN H. · 2012 to 2018
$131.5MHOPE Training GrantT32AI007384 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sara Gianella Weibel, Scott L Letendre · 1990 to 2026
$9.7MRESEARCH IN INFECTIOUS DISEASEST32AI007036 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR · 1985 to 2025
$9.2MGAS Switch from Colonizing Bacterium to Invasive PathogenR01AI077780 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR · 2008 to 2019
$3.8MCD4 T cell, germinal center, and antibody response defects in recurrent tonsillitisR01AI135193 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P · 2018 to 2022
$2.3MThe Immunology of Recurrent Group A Streptococcus TonsillitisK08AI135078 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAN, JENNIFER MARIE · 2018 to 2022
$972kIllumina HiSeq 2500 Sequencing SystemS10OD016262 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI RAO, ANJANA · 2013 to 2013
$600kFACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514kCancer Research UK 15951Medical Research Council MR/P024351/1NCRR NIH HHS S10 RR027366NIAID NIH HHS K08 AI135078NIAID NIH HHS L40 AI126497NIAID NIH HHS R01 AI077780NIAID NIH HHS R01 AI135193NIAID NIH HHS T32 AI007036NIAID NIH HHS T32 AI007384NIAID NIH HHS UM1 AI100663NIH HHS S10 OD016262
Abstract
"Strep throat" is highly prevalent among children, yet it is unknown why only some children develop recurrent tonsillitis (RT), a common indication for tonsillectomy. To gain insights into this classic childhood disease, we performed phenotypic, genotypic, and functional studies on pediatric group A
Indexed as
AdolescentAllelesAntibodies, BacterialB-LymphocytesCell DifferentiationChildDisease SusceptibilityFemaleGerminal CenterGranzymesHistocompatibility Antigens Class IIHumansImmunoglobulin GMaleRecurrenceStreptococcusAntibodies, BacterialGranzymesHistocompatibility Antigens Class IIImmunoglobulin GSuperantigens
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.