Evidence map›Paper›PMID 30728284›Full record

ArticlemSphere2019

The Vacuolar Ca

Arturo Luna-Tapia, Christian DeJarnette, Emily Sansevere, Parker Reitler, Arielle Butts, Kirk E Hevener, Glen E Palmer

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Phenotypic and genotypic analysis ofInfection and immunity · 2026
    Article
  2. The coupling effect ofSynthetic and systems biotechnology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. The Effect of Honokiol on Ergosterol Biosynthesis and Vacuole Function inJournal of microbiology and biotechnology · 2020
    Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Arturo Luna-Tapia *Department of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Christian DeJarnette *Department of Molecular Immunology and Biochemistry, College of Graduate Health Sciences, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Emily SansevereDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Parker ReitlerDepartment of Molecular Immunology and Biochemistry, College of Graduate Health Sciences, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Arielle ButtsDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Kirk E HevenerDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.
Glen E PalmerDepartment of Clinical Pharmacy and Translational Science, College of Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA gpalmer5@uthsc.edu.
University of Tennessee Health Science Center · US

Funding

Molecular and chemical validation of the vacuole as a new antifungal targetR01AI099080 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PALMER, GLEN · 2014 to 2018
$1.9M
NIAID NIH HHS R01 AI099080
6 · The paper itself

Abstract

Calcium is a critically important secondary messenger of intracellular signal transduction in eukaryotes but must be maintained at low levels in the cytoplasm of resting cells to avoid toxicity. This is achieved by several pumps that actively transport excess cytoplasmic Ca

Indexed as

AnimalsAntifungal AgentsAzolesBiofilmsCandida albicansCandidiasis, InvasiveDrug Resistance, FungalFungal ProteinsHyphaeMiceMice, Inbred BALB CPlasma Membrane Calcium-Transporting ATPasesTemperatureVacuolar Proton-Translocating ATPasesVirulenceAntifungal AgentsAzolesFungal ProteinsPlasma Membrane Calcium-Transporting ATPasesVacuolar Proton-Translocating ATPasescalciumCandida albicanspathogenesisPmc1pvacuoleVcx1p

Identifiers

PMID30728284
PMCPMC6365616
OpenAlexW2914904782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.