Evidence map›Paper›PMID 30728262›Full record

ArticleJournal of virology2019

Infectious Herpes Simplex Virus in the Brain Stem Is Correlated with Reactivation in the Trigeminal Ganglia.

Jessica R Doll, Richard L Thompson, Nancy M Sawtell

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Modeling infectious diseases of the central nervous system with human brain organoids.Translational research : the journal of laboratory and clinical medicine · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Frontiers in cellular and infection microbiology · 2022
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jessica R DollUniversity of Cincinnati, Department of Molecular Genetics, Biochemistry, and Microbiology, Cincinnati, Ohio, USA jessica.doll@cchmc.org.ORCID 0000-0001-5225-801X
Richard L ThompsonUniversity of Cincinnati, Department of Molecular Genetics, Biochemistry, and Microbiology, Cincinnati, Ohio, USA.
Nancy M SawtellCincinnati Children's Hospital Medical Center, Division of Infectious Diseases, Cincinnati, Ohio, USA.
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

HSV latency and reactivation and the novel neuronal regulation of VP16 in vivo.R01AI093614 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SAWTELL, NANCY M. · 2012 to 2016
$2.5M
NIAID NIH HHS R01 AI093614
6 · The paper itself

Abstract

Herpes simplex virus (HSV) establishes latency in neurons of the peripheral and central nervous systems (CNS). Evidence is mounting that HSV latency and reactivation in the nervous system has the potential to promote neurodegenerative processes. Understanding how this occurs is an important human health goal. In the mouse model,

Indexed as

AnimalsBiological Transport, ActiveBrain StemFemaleHerpes SimplexHerpesvirus 1, HumanMaleMiceRabbitsTrigeminal GanglionViral ProteinsVirus ActivationVirus LatencyViral Proteinshypercellular cuffhyperthermic stressin vivo reactivationmouse ocular modelsensory neuronviral latencyvirus recovery

Identifiers

PMID30728262
PMCPMC6450102
OpenAlexW2911984595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.