Evidence map›Paper›PMID 30728215›Full record

ArticleThe Journal of general physiology2019

The binding interactions that maintain excitation-contraction coupling junctions in skeletal muscle.

Eduardo Ríos, Dirk Gillespie, Clara Franzini-Armstrong

Open access · hybridAbstract read
In one paragraph

Article in The Journal of general physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. A Review of the Role of Endo/Sarcoplasmic Reticulum-Mitochondria CaInternational journal of environmental research and public health · 2021
    Review
  7. CaCells · 2019
    Review
  8. Ionic channels in nerve membranes, 50 years on.Progress in biophysics and molecular biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eduardo RíosSection of Cellular Signaling, Department of Physiology and Biophysics, Rush University, Chicago, IL erios@rush.edu.ORCID 0000-0003-0985-8997
Dirk GillespieSection of Cellular Signaling, Department of Physiology and Biophysics, Rush University, Chicago, IL.ORCID 0000-0003-0802-5352
Clara Franzini-ArmstrongDepartment of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA armstroc@pennmedicine.upenn.edu.
Rush University · USUniversity of Pennsylvania · US

Funding

Mechanisms of couplon-linked skeletal muscle myopathiesR01AR072602 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI HAMILTON, SUSAN L, HORRIGAN, FRANK T · 2018 to 2022
$3.3M
The HH: A Large Cohort of Patients with Congenital Myopathies of Uncertain EtiologyR01AR071381 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI FILL, MICHAEL, RIAZI, SHEILA · 2017 to 2021
$2.7M
Roles of Calsequestrin in the Control of Calcium Signals in Health and DiseaseR01GM111254 · NIGMS · RUSH UNIVERSITY MEDICAL CENTER · PI KANG, CHULHEE, RIOS, EDUARDO · 2014 to 2017
$1.4M
Dual Confocal Microscopic ScannerS10RR024707 · NCRR · RUSH UNIVERSITY MEDICAL CENTER · PI RIOS, EDUARDO · 2008 to 2008
$500k
NCRR NIH HHS S10 RR024707NIAMS NIH HHS R01 AR071381NIAMS NIH HHS R01 AR072602NIGMS NIH HHS R01 GM111254
6 · The paper itself

Abstract

Calcium for contraction of skeletal muscles is released via tetrameric ryanodine receptor (RYR1) channels of the sarcoplasmic reticulum (SR), which are assembled in ordered arrays called couplons at junctions where the SR abuts T tubules or plasmalemma. Voltage-gated Ca

Indexed as

Computer SimulationMonte Carlo MethodMuscle, SkeletalAnimalsCalcium ChannelsMuscle ContractionProtein BindingCalcium Channels

Identifiers

PMID30728215
PMCPMC6445584
OpenAlexW2914040488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.