Evidence map›Paper›PMID 30728194›Full record

ReviewJournal of clinical microbiology2019

Phylogenomic Pipeline Validation for Foodborne Pathogen Disease Surveillance.

Ruth E Timme, Errol Strain, Joseph D Baugher, Steven Davis, Narjol Gonzalez-Escalona, Maria Sanchez Leon, Marc W Allard, Eric W Brown, Sandra Tallent, Hugh Rand

Open access · bronzeAbstract readReviewValidation Study
In one paragraph

Review in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  11. Journal of fungi (Basel, Switzerland) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ruth E TimmeCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA ruth.timme@fda.hhs.gov.ORCID 0000-0002-9705-5897
Errol StrainCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Joseph D BaugherCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Steven DavisCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Narjol Gonzalez-EscalonaCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.ORCID 0000-0003-4568-0022
Maria Sanchez LeonCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Marc W AllardCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Eric W BrownCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Sandra TallentCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Hugh RandCenter for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Center for Food Safety and Applied Nutrition · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foodborne pathogen surveillance in the United States is transitioning from strain identification using restriction digest technology (pulsed-field gel electrophoresis [PFGE]) to shotgun sequencing of the entire genome (whole-genome sequencing [WGS]). WGS requires a new suite of analysis tools, some of which have long histories in academia but are new to the field of public health and regulatory decision making. Although the general workflow is fairly standard for collecting and analyzing WGS data for disease surveillance, there are a number of differences in how the data are collected and analyzed across public health agencies, both nationally and internationally. This impedes collaborative public health efforts, so national and international efforts are underway to enable direct comparison of these different analysis methods. Ultimately, the harmonization efforts will allow the (mutually trusted and understood) production and analysis of WGS data by labs and agencies worldwide, thus improving outbreak response capabilities globally. This review provides a historical perspective on the use of WGS for pathogen tracking and summarizes the efforts underway to ensure the major steps in phylogenomic pipelines used for pathogen disease surveillance can be readily validated. The tools for doing this will ensure that the results produced are sound, reproducible, and comparable across different analytic approaches.

Indexed as

Data AnalysisPhylogenyBacteriaComputational BiologyDisease OutbreaksElectrophoresis, Gel, Pulsed-FieldEpidemiological MonitoringFoodborne DiseasesGenome, BacterialHumansPublic HealthUnited StatesWhole Genome Sequencingbioinformatic pipelinefoodborne pathogenListeriaoutbreakphylogenySalmonellavalidationWGS

Identifiers

PMID30728194
PMCPMC6498022
OpenAlexW2911751759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.