Evidence map›Paper›PMID 30728156›Full record

ArticleGenetics2019

Modulation of Gene Silencing by Cdc7p via H4 K16 Acetylation and Phosphorylation of Chromatin Assembly Factor CAF-1 in

Tiffany J Young, Yi Cui, Joseph Irudayaraj, Ann L Kirchmaier

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tiffany J YoungDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907.
Yi CuiPurdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907.
Joseph IrudayarajPurdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907.
Ann L KirchmaierDepartment of Biochemistry, Purdue University, West Lafayette, Indiana 47907 kirchmaier@purdue.edu.ORCID 0000-0001-9938-9105
Center for Cancer Research · USPurdue University West Lafayette · US

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI ANDREW D MESECAR · 1985 to 2026
$43.4M
NCI NIH HHS P30 CA023168
6 · The paper itself

Abstract

CAF-1 is an evolutionarily conserved H3/H4 histone chaperone that plays a key role in replication-coupled chromatin assembly and is targeted to the replication fork via interactions with PCNA, which, if disrupted, leads to epigenetic defects. In

Indexed as

Gene SilencingHistone CodeAcetylationCell Cycle ProteinsChromatin Assembly Factor-1Gene Expression Regulation, FungalHistonesPhosphorylationProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCDC7 protein, S cerevisiaeCell Cycle ProteinsChromatin Assembly Factor-1HistonesProtein Serine-Threonine KinasesRLF2 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsCAC1CAF-1CDC7histone H4 K16SAS2silencing

Identifiers

PMID30728156
PMCPMC6456304
OpenAlexW2912047635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.