Evidence map›Paper›PMID 30727982›Full record

Trial reportBMC ophthalmology2019

Combined phacoemulsification and viscocanalostomy with Ologen implant versus combined phacoemulsification and viscocanalostomy.

Ahmed A M Gad, Bahaa-Eldin Hasan Abdulhalim, Ayman Lotfy, Ayman Mohamed Abdelrahman, Ahmed Samir Ahmed

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03782051 (Combined Phacoemulsification and Viscocanalostomy With Ologen Implant Versus Combined Phacoemulsification and Viscocanalostomy), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03782051 nacompletednot on this map

Combined Phacoemulsification and Viscocanalostomy With Ologen Implant Versus Combined Phacoemulsification and Viscocanalostomy

TypeinterventionalSponsorZagazig UniversityRan2013 to 2018Enrolled81ConditionsPrimary Open-angle GlaucomaArmscombined phacoemulsification and viscocanalostomy, combined phacoemulsification and viscocanalostomy and ologen
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ahmed A M GadOphthalmology Department, Zagazig University, Zagazig, 44511, Egypt. ahmedmoemen@yahoo.com.ORCID http://orcid.org/0000-0002-4786-4987
Bahaa-Eldin Hasan AbdulhalimOphthalmology Department, Shaqra University/Zagazig University, Shaqraa, Kingdom of Saudi Arabia.
Ayman LotfyOphthalmology Department, Zagazig University, Zagazig, 44511, Egypt.
Ayman Mohamed AbdelrahmanOphthalmology Department, Zagazig University, Zagazig, 44511, Egypt.
Ahmed Samir AhmedOphthalmology Department, Zagazig University, Zagazig, 44511, Egypt.
Zagazig University · EGShaqra University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo study the efficacy of the biodegradable collagen implant Ologen® as an adjuvant in phaco-viscocanalostomy in patients with coexisting cataract and primary open angle glaucoma.

methodsThis prospective, interventional, randomized clinical study was done at Alpha Vision Center, Zagazig, Egypt. Patients with coexisting cataract and glaucoma were randomized to receive either phaco-viscocanalostomy (Phacovisco group) (39 eyes) or phaco-viscocanalostomy with Ologen® implant (OloPhacovisco group) (40 eyes). Follow-up period was 2 years. Nd:YAG laser goniopuncture was done in cases where the intraocular pressure (IOP) was elevated above 21 mmHg after discontinuation of corticosteroid eye drops at any follow-up visit.

resultsNo significant operative or postoperative complications (other than failure) were encountered in either group. At 2 years follow-up, the mean IOP level was statistically significantly decreased in the OloPhacovisco group (p = 0.02) and complete success occurred in 23 eyes (59.0%) in the Phacovisco group and in 32 eyes (80.0%) in the OloPhacovisco group. There was a statistically significant higher success rate regarding complete success in patients that received Ologen® implant (p = 0.04).

conclusionsOlogen® implant improved the success rate of phaco-viscocanalostomy. Larger studies with longer follow-up periods may be required to confirm these findings.

trial registrationThis trial was retrospectively registered on 20/12/2018 under the number ( NCT03782051 ).

Indexed as

AdultAgedAged, 80 and overCataractCollagenFemaleFiltering SurgeryGlaucoma, Open-AngleGlycosaminoglycansHumansIntraocular PressureMaleMiddle AgedPhacoemulsificationProspective StudiesCollagencollagen-glycosaminoglycan copolymerGlycosaminoglycansGlaucomaOlogenPhacoemulsificationViscocanalostomy

Identifiers

PMID30727982
PMCPMC6364460
OpenAlexW2911781443

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.