ArticleBMC genomics2019
Genome expansion of an obligate parthenogenesis-associated Wolbachia poses an exception to the symbiont reduction model.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Genomic evolution and adaptation of arthropod-associated Rickettsia.Scientific reports · 2022Pooled it
- Analysis of the genomes of a male-killingMicrobial genomics · 2026Article
- A co-speciation dilemma and a lifestyle transition with genomic consequences in Wolbachia of Neotropical Drosophila.BMC genomics · 2025Article
- crANKing up the infection: ankyrin domains inInfection and immunity · 2024Review
- Describing endosymbiont-host interactions within the parasitism-mutualism continuum.Ecology and evolution · 2024Article
- Identification of Parthenogenesis-Inducing Effector Proteins in Wolbachia.Genome biology and evolution · 2024Article
- Virus-like Particles fromInsects · 2023Article
- Article
- Widespread phages of endosymbionts: Phage WO genomics and the proposed taxonomic classification of Symbioviridae.PLoS genetics · 2022Article
- Living in the endosymbiotic world of Wolbachia: A centennial review.Cell host & microbe · 2021Review
- DNA recombination and repair in Wolbachia: RecA and related proteins.Molecular genetics and genomics : MGG · 2021Article
- Evolution of genome structure in theGenome research · 2021Article
- Diminutive, degraded but dissimilar:Microbial genomics · 2020Article
- An Earliest Endosymbiont,International journal of molecular sciences · 2020Article
- Wolbachia and Sirtuin-4 interaction is associated with alterations in host glucose metabolism and bacterial titer.PLoS pathogens · 2020Article
- Computational evidence for antitoxins associated with RelE/ParE, RatA, Fic, and AbiEii-family toxins in Wolbachia genomes.Molecular genetics and genomics : MGG · 2020Article
- Pseudoscorpion Wolbachia symbionts: diversity and evidence for a new supergroup S.BMC microbiology · 2020Article
- Genomic Analysis of Wolbachia from Laodelphax striatellus (Delphacidae, Hemiptera) Reveals Insights into Its "Jekyll and Hyde" Mode of Infection Pattern.Genome biology and evolution · 2020Article
- Evolution ofPeerJ · 2020Article
- The Wolbachia Symbiont: Here, There and Everywhere.Results and problems in cell differentiation · 2020Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundTheory predicts that dependency within host-endosymbiont interactions results in endosymbiont genome size reduction. Unexpectedly, the largest Wolbachia genome was found in the obligate, parthenogenesis-associated wFol. In this study, we investigate possible processes underlying this genome expansion by comparing a re-annotated wFol genome to other Wolbachia genomes. In addition, we also search for candidate genes related to parthenogenesis induction (PI).
resultsWithin wFol, we found five phage WO regions representing 25.4% of the complete genome, few pseudogenized genes, and an expansion of DNA-repair genes in comparison to other Wolbachia. These signs of genome conservation were mirrored in the wFol host, the springtail F. candida, which also had an expanded DNA-repair gene family and many horizontally transferred genes. Across all Wolbachia genomes, there was a strong correlation between gene numbers of Wolbachia strains and their hosts. In order to identify genes with a potential link to PI, we assembled the genome of an additional PI strain, wLcla. Comparisons between four PI Wolbachia, including wFol and wLcla, and fourteen non-PI Wolbachia yielded a small set of potential candidate genes for further investigation.
conclusionsThe strong similarities in genome content of wFol and its host, as well as the correlation between host and Wolbachia gene numbers suggest that there may be some form of convergent evolution between endosymbiont and host genomes. If such convergent evolution would be strong enough to overcome the evolutionary forces causing genome reduction, it would enable expanded genomes within long-term obligate endosymbionts.
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