Evidence map›Paper›PMID 30727742›Full record

Trial reportCNS oncology2019

A feasibility study of the Nativis Voyager

Michael Murphy, Anthony Dowling, Christopher Thien, Emma Priest, Donna Morgan Murray, Santosh Kesari

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in CNS oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Neuromodulation in Neuro-Oncology: A Scoping Review.Journal of personalized medicine · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Welcome to Volume 9 ofCNS oncology · 2020
    Article
  7. Article
  8. How far will the VoyagerCNS oncology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Michael MurphyDepartment of Neurosurgery, St Vincent's Hospital, Fitzroy, Australia.
Anthony DowlingDepartment of Oncology, St Vincent's Hospital, Fitzroy, Australia.
Christopher ThienDepartment of Neurosurgery, St Vincent's Hospital, Fitzroy, Australia.
Emma PriestDepartment of Neurosurgery, St Vincent's Hospital, Fitzroy, Australia.
Donna Morgan MurrayNativis, Inc., Department of Clinical and Regulatory Affairs, Seattle, WA 98109, USA.
Santosh KesariJohn Wayne Cancer Institute & Pacific Neuroscience Institute, Department of Translational Neurooncology and Neurotherapeutics, Santa Monica, CA, 90404, USA.
St Vincent's Hospital · AUUniversity of Melbourne · AUKharkiv National University of Internal Affairs · UASaint John's Health Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimEvaluation of the Nativis Voyager MATERIALS &

methodsA total of 15 patients with rGBM were treated with one of two Voyager ultra-low radio frequency energy cognates: A1A or A2HU. Safety and clinical utility were assessed every 2-4 months.

resultsMedian overall survival was 8.04 months in the A1A arm and 6.89 months in the A2HU arm. No serious adverse events associated with Voyager were reported. No clinically relevant trends were noted in clinical laboratory parameters or physical exams.

conclusionThe data suggest that the Voyager is safe and feasible for the treatment of rGBM.

Indexed as

Magnetic Field TherapyAdultAgedAustraliaBrain NeoplasmsFeasibility StudiesFemaleGlioblastomaHumansMaleMiddle AgedNeoplasm Recurrence, LocalTreatment Outcomebrain cancerclinical trialelectromagnetic fieldsglioblastomamedical deviceNativis Voyagerrecurrent GBM

Identifiers

PMID30727742
PMCPMC6499017
OpenAlexW2911293308

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.