Evidence map›Paper›PMID 30726937›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2019

Omnipolarity applied to equi-spaced electrode array for ventricular tachycardia substrate mapping.

Andreu Porta-Sánchez, Karl Magtibay, Sachin Nayyar, Abhishek Bhaskaran, Patrick F H Lai, Stéphane Massé, Christopher Labos, Beiping Qiang, Rocco Romagnuolo, Hassan Masoudpour and 5 more

Abstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Contemporary Management of Complex Ventricular Arrhythmias.Arrhythmia & electrophysiology review · 2022
    Review
  13. Initial experience of the High-Density Grid catheter in patients undergoing catheter ablation for atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022
    Article
  14. Article
  15. Article
  16. Review
  17. Updates in Ventricular Tachycardia Ablation.Korean circulation journal · 2021
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andreu Porta-SánchezDept de Medicina, Universitat de Barcelona, Barcelona and Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
Karl MagtibayDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Sachin NayyarDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Abhishek BhaskaranDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Patrick F H LaiDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Stéphane MasséDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Christopher LabosOffice for Science and Society, McGill University, Montreal, Quebec, Canada.
Beiping QiangDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Rocco RomagnuoloDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Hassan MasoudpourDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Labonny BiswasSunnybrook Research Institute, Toronto, Ontario, Canada.
Nilesh GhugreSunnybrook Research Institute, Toronto, Ontario, Canada.
Michael LaflammeDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
Don Curtis DenoApplied Research, Abbott Laboratories, St Paul, MN, USA.
Kumaraswamy NanthakumarDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsBipolar electrogram (BiEGM)-based substrate maps are heavily influenced by direction of a wavefront to the mapping bipole. In this study, we evaluate high-resolution, orientation-independent peak-to-peak voltage (Vpp) maps obtained with an equi-spaced electrode array and omnipolar EGMs (OTEGMs), measure its beat-to-beat consistency, and assess its ability to delineate diseased areas within the myocardium compared against traditional BiEGMs on two orientations: along (AL) and across (AC) array splines. METHODS AND

resultsThe endocardium of the left ventricle of 10 pigs (three healthy and seven infarcted) were each mapped using an Advisor™ HD grid with a research EnSite Precision™ system. Cardiac magnetic resonance images with late gadolinium enhancement were registered with electroanatomical maps and were used for gross scar delineation. Over healthy areas, OTEGM Vpp values are larger than AL bipoles by 27% and AC bipoles by 26%, and over infarcted areas OTEGM Vpp values are 23% larger than AL bipoles and 27% larger than AC bipoles (P < 0.05). Omnipolar EGM voltage maps were 37% denser than BiEGM maps. In addition, OTEGM Vpp values are more consistent than bipolar Vpps showing less beat-by-beat variation than BiEGM by 39% and 47% over both infarcted and healthy areas, respectively (P < 0.01). Omnipolar EGM better delineate infarcted areas than traditional BiEGMs from both orientations.

conclusionAn equi-spaced electrode grid when combined with omnipolar methodology yielded the largest detectable bipolar-like voltage and is void of directional influences, providing reliable voltage assessment within infarcted and non-infarcted regions of the heart.

Indexed as

CicatrixElectrophysiologic Techniques, CardiacMyocardial InfarctionTachycardia, VentricularAnimalsElectrocardiographyHeartMyocardiumPrognosisSwineBipolarElectroanatomic mappingElectrogramMyocardial infarctionOmnipolarPorcineUnipolarVoltage

Identifiers

PMID30726937
PMCPMC6479413

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.