Evidence map›Paper›PMID 30726913›Full record

ArticleInflammatory bowel diseases2019

A Longitudinal Study of Sexual Function in Women With Newly Diagnosed Inflammatory Bowel Disease.

Eugenia Shmidt, Mayte Suárez-Fariñas, Meaghan Mallette, Heather Moniz, Renee Bright, Samir A Shah, Marjorie Merrick, Jason Shapiro, Fang Xu, Bruce Sands and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inflammatory bowel diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Sexual dysfunction is highly prevalent in patients with active perianal fistulizing Crohn's disease: Outcomes from a large national prospective cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
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  10. Associations with sexual dysfunction among a Canadian cohort with inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025
    Article
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  13. Patient experiences in ulcerative colitis: conceptual model and review of patient-reported outcome measures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Eugenia ShmidtDr Henry D Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; University of Minnesota, Division of Gastroenterology, Hepatology and Nutrition, Minneapolis, Minnesota, USA.
Mayte Suárez-FariñasDepartment of Population Health Science and Policy, Department of Genetics and Genomics Science, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Meaghan MalletteRhode Island Hospital, Providence, Rhode Island, USA.
Heather MonizRhode Island Hospital, Providence, Rhode Island, USA.
Renee BrightRhode Island Hospital, Providence, Rhode Island, USA.
Samir A ShahThe Warren Alpert Medical School at Brown University, Providence, Rhode Island, USA.
Marjorie MerrickCrohn's & Colitis Foundation of America (retired), New York, New York, USA.
Jason ShapiroDivision of Pediatric Gastroenterology, Nutrition, and Liver Diseases, Hasbro Children's Hospital, Providence, Rhode Island, USA.
Fang XuDivision of Population Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Bruce SandsDr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Sumona SahaDivision of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Rhode Island Hospital · USIcahn School of Medicine at Mount Sinai · USBrown University · USCenters for Disease Control and Prevention · USCrohn's and Colitis Foundation · USProvidence College · USUniversity of Minnesota · USUniversity of Wisconsin–Madison · US

Funding

Practice Variation in Management of Inflammatory Bowel DiseaseU01DP000340 · DP · CROHN'S AND COLITIS FDN OF AMERICA, INC. · PI MERRICK, MARJORIE · 2005 to 2009
$2.1M
OSCCAR: Ocean State Crohn's and Colitis Area RegistryU01DP002676 · DP · CROHN'S AND COLITIS FDN OF AMERICA, INC. · PI MERRICK, MARJORIE · 2010 to 2012
$794k
Intramural CDC HHS CC999999NCCDPHP CDC HHS U01 DP000340NCCDPHP CDC HHS U01 DP002676
6 · The paper itself

Abstract

backgroundThe literature provides conflicting data on sexual function in women with inflammatory bowel disease (IBD). We aim to describe sexual function at baseline and over time in a prospective inception cohort of adult women with IBD.

methodsWomen age 18 years or older enrolled in the Ocean State Crohn's & Colitis Area Registry (OSCCAR) with 2 years of prospective follow-up were included in the study. All subjects were enrolled within 1 year of IBD diagnosis. Female sexual function was assessed using the Female Sexual Function Index (FSFI). Linear mixed effects models were used to assess changes in FSFI by various demographic and clinical factors.

resultsOne hundred sixteen of 130 eligible women (89%) were included in the study. Ninety-seven percent of women had sexual dysfunction, defined as an FSFI score of <26.55, with a baseline mean FSFI score (SD) of 16.4 (8.4) overall (15.5 [8.6] in Crohn's disease, 17.4 [8.1] in UC, P = 0.22). Despite improvement in overall disease activity, there was no significant change in the FSFI score or individual domain scores over the entire 2-year study period. Among all women with IBD, older age, nonsingle marital status, lower Short Form Health Survey (SF-36) Physical Component Summary score, and the use of biologics were independent risk factors for sexual dysfunction.

conclusionsAlmost all women experienced sexual dysfunction that did not improve over time despite improvement in overall disease activity. Future studies are warranted to identify underlying mechanisms that explain the associations between demographic and clinical factors and sexual dysfunction among newly diagnosed women.

Indexed as

Severity of Illness IndexAdolescentAdultAgedFemaleFollow-Up StudiesHumansInflammatory Bowel DiseasesLongitudinal StudiesMiddle AgedPrognosisProspective StudiesRegistriesRisk FactorsSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalCrohn’s diseasequality of lifesexual functionulcerative colitis

Identifiers

PMID30726913
PMCPMC11079919
OpenAlexW2913036705

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.