Evidence map›Paper›PMID 30726800›Full record

ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2019

MR Imaging Properties of ex vivo Common Marmoset Brain after Formaldehyde Fixation.

Yawara Haga, Junichi Hata, Akiko Uematsu, Fumiko Seki, Yuji Komaki, Mai Mizumura, Marin Nishio, Takaaki Kaneko, Noriyuki Kishi, Hideyuki Okano and 1 more

Abstract read
In one paragraph

Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Effects of Postmortem Intervals on Quantitative MRI in Unfixed and Fixed Swine Brain: Implications for Ex Vivo MRI Applications.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Influence of Diffusion Time and Temperature on Restricted Diffusion Signal: A Phantom Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Demonstration of Human Fetal Bone Morphology with MR Imaging: A Preliminary Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yawara HagaDepartment of Radiological Sciences, Human Health Sciences, Tokyo Metropolitan University Graduate School.
Junichi HataDepartment of Physiology, Keio University School of Medicine.
Akiko UematsuDepartment of Physiology, Keio University School of Medicine.
Fumiko SekiDepartment of Physiology, Keio University School of Medicine.
Yuji KomakiDepartment of Physiology, Keio University School of Medicine.
Mai MizumuraDepartment of Radiological Sciences, Human Health Sciences, Tokyo Metropolitan University Graduate School.
Marin NishioDepartment of Radiological Sciences, Human Health Sciences, Tokyo Metropolitan University Graduate School.
Takaaki KanekoDepartment of Physiology, Keio University School of Medicine.
Noriyuki KishiDepartment of Physiology, Keio University School of Medicine.
Hideyuki OkanoDepartment of Physiology, Keio University School of Medicine.
Akira FurukawaDepartment of Radiological Sciences, Human Health Sciences, Tokyo Metropolitan University Graduate School.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEx vivo brains have different MRI properties than in vivo brains because of chemical changes caused by fixative solutions, which change the signal intensity and/or tissue contrast on MR images. In this study, we investigated and compared the MRI properties of in vivo and ex vivo brains.

methodsUsing a Bruker 9.4T experimental scanner unit for animals (Biospin GmbH, Ettlingen, Germany), we performed this study on the common marmoset. We measured the relaxation and diffusion values in the white matter and cortex of common marmosets and compared these values between in vivo brains (n = 20) and ex vivo brains (n = 20). Additionally, we observed the relationship between the tissue fixation duration and MRI properties by imaging a brain that underwent long-term fixation in a preliminary examination (n = 1).

resultsThe T

conclusionThe T

Indexed as

AnimalsBrainCallithrixFormaldehydeMagnetic Resonance ImagingTissue FixationFormaldehydecommon marmosetdiffusion propertiespostmortem magnetic resonance imagingrelaxation time

Identifiers

PMID30726800
PMCPMC6883083

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.