Evidence map›Paper›PMID 30726715›Full record

ArticleNeuroscience letters2019

NMDA receptor deletion on dopamine neurons disrupts visual discrimination and reversal learning.

Anna K Radke, Larry S Zweifel, Andrew Holmes

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Anna K RadkeDepartment of Psychology and Center for Neuroscience and Behavior, Miami University, Oxford, OH, USA. Electronic address: aradke@miamioh.edu.
Larry S ZweifelDepartments of Psychiatry and Behavioral Science & Pharmacology, University of Washington, Seattle, WA, USA.
Andrew HolmesLaboratory of Behavioral and Genomic Neuroscience, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA.
Miami University · USNational Institutes of Health · USUniversity of Washington · US

Funding

Mouse models of stress disorders and addictionZIAAA000411 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI HOLMES, ANDREW · 2009 to 2025
$37.7M
Functional Mapping of Dopamine-Dependent Fear Circuitry Through Advanced GeneticR01MH094536 · NIMH · UNIVERSITY OF WASHINGTON · PI ZWEIFEL, LARRY S · 2011 to 2015
$2.3M
Intramural NIH HHS ZIA AA000411NIMH NIH HHS R01 MH094536
6 · The paper itself

Abstract

The dopamine (DA) system is critical for various forms of learning about salient environmental stimuli. Prior work has shown that deletion of the obligatory NR1 subunit of the N-methyl-

Indexed as

AnimalsDiscrimination, PsychologicalDopaminergic NeuronsFemaleMaleMiceMice, Neurologic MutantsPhotic StimulationReceptors, N-Methyl-D-AspartateReversal LearningVisual PerceptionReceptors, N-Methyl-D-AspartateBehavioral flexibilityCognitive flexibilityDiscriminationDopamineLearningMutant mouseNMDA receptorNR1 subunitReversalTouchscreen

Identifiers

PMID30726715
PMCPMC6534146
OpenAlexW2914936771

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.