Evidence map›Paper›PMID 30726661›Full record

ArticleMolecules and cells2019

Alleviation of Senescence via ATM Inhibition in Accelerated Aging Models.

Myeong Uk Kuk, Jae Won Kim, Young-Sam Lee, Kyung A Cho, Joon Tae Park, Sang Chul Park

Open access · greenAbstract read
In one paragraph

Article in Molecules and cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

  1. Aging and cancer: current understandings and future perspectives.Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Review
  4. Senotherapy for chronic lung disease.Pharmacological reviews · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels.Frontiers in cell and developmental biology · 2022
    Article
  16. Review
  17. Preclinical Advances of Therapies for Laminopathies.Journal of clinical medicine · 2021
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Myeong Uk KukDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, Korea.
Jae Won KimDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, Korea.
Young-Sam LeeWell Aging Research Center, Daegu, Korea.
Kyung A ChoDepartment of Biochemistry, Chonnam National University Medical School, Gwangju, Korea.
Joon Tae ParkDivision of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Incheon, Korea.
Sang Chul ParkWell Aging Research Center, Daegu, Korea.
Incheon National University · KRChonnam National University · KRDaegu Gyeongbuk Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The maintenance of mitochondrial function is closely linked to the control of senescence. In our previous study, we uncovered a novel mechanism in which senescence amelioration in normal aging cells is mediated by the recovered mitochondrial function upon

Indexed as

Cellular SenescenceModels, BiologicalAgingAtaxia Telangiectasia Mutated ProteinsCell Nucleus ShapeDNA Breaks, Double-StrandedFibroblastsHumansLamin Type AMitochondriaProgeriaAtaxia Telangiectasia Mutated ProteinsLamin Type Aprelamin AATM inhibitionHGPSKU-60019mitochondrial functionWS

Identifiers

PMID30726661
PMCPMC6449716
OpenAlexW2970534187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.