Evidence map›Paper›PMID 30726268›Full record

Trial reportPloS one2019

The effects of heated humidification to nasopharynx on nasal resistance and breathing pattern.

Yukio Fujita, Motoo Yamauchi, Hiroki Uyama, Hideshi Oda, Michihito Igaki, Masanori Yoshikawa, Hiroshi Kimura

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Warm Steam Inhalation before Bedtime Improved Sleep Quality in Adult Men.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yukio FujitaSecond Department of Internal Medicine (Department of Respiratory Medicine), Nara Medical University, Kashihara, Japan.ORCID 0000-0002-4308-2275
Motoo YamauchiSecond Department of Internal Medicine (Department of Respiratory Medicine), Nara Medical University, Kashihara, Japan.
Hiroki UyamaSecond Department of Internal Medicine (Department of Respiratory Medicine), Nara Medical University, Kashihara, Japan.
Hideshi OdaPersonal Health Care Products Research Laboratories, Kao Corporation, Tokyo, Japan.
Michihito IgakiPersonal Health Care Products Research Laboratories, Kao Corporation, Tokyo, Japan.
Masanori YoshikawaSecond Department of Internal Medicine (Department of Respiratory Medicine), Nara Medical University, Kashihara, Japan.
Hiroshi KimuraDepartment of Advanced Medicine for Pulmonary Circulation and Respiratory Failure, and Department of Pulmonary Medicine, Nippon Medical School Graduate School of Medicine, Tokyo, Japan.
Nara Medical University · JPKao Corporation (Japan) · JPNippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMouth breathing could induce not only dry throat and eventually upper respiratory tract infection, but also snoring and obstructive sleep apnea, while nasal breathing is protective against those problems. Thus, one may want to explore an approach to modify habitual mouth breathing as preferable to nasal breathing. The aim of this study was to investigate the physiological effects of our newly developed mask on facilitation of nasal breathing.

methodsThirty seven healthy male volunteers were enrolled in a double blind, randomized, placebo-controlled crossover trial. Participants wore a newly developed heated humidification mask or non-heated-humidification mask (placebo) for 10-min each. Subjective feelings including dry nose, dry throat, nasal obstruction, ease to breathe, relaxation, calmness, and good feeling were asked before and after wearing each mask. In addition, the effects of masks on nasal resistance, breathing pattern, and heart rate variability were assessed.

resultsCompared with the placebo mask, the heated humidification mask improved all components of subjective feelings except for ease to breathe; moreover, decreased nasal resistance and respiratory frequency accompanied a simultaneous increase in a surrogate maker for tidal volume. However, use of the heated humidification mask did not affect heart rate variability.

conclusionAdding heated humidification to the nasopharynx could modulate breathing patterns with improvement of subjective experience and objective nasal resistance.

Indexed as

HumidityRespirationAdultCross-Over StudiesDouble-Blind MethodHealthy VolunteersHot TemperatureHumansMaleMasksMiddle AgedMouth BreathingNasopharynx

Identifiers

PMID30726268
PMCPMC6364899
OpenAlexW2913044273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.