Evidence map›Paper›PMID 30726185›Full record

ArticleStroke2019

Real-World Treatment Trends in Endovascular Stroke Therapy.

Hamidreza Saber, Babak B Navi, James C Grotta, Hooman Kamel, Arvind Bambhroliya, Farhaan S Vahidy, Peng Roc Chen, Spiros Blackburn, Sean I Savitz, Louise McCullough and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Revisiting Western Aphasia Battery-Revised in the Context of Mild Impairment.American journal of speech-language pathology · 2026
    Article
  9. Virtual reality simulation training in stroke thrombectomy centers with limited patient volume-Simulator performance and patient outcome.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Racial and ethnic disparities in the usage and outcomes of ischemic stroke treatment in the United States.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hamidreza SaberFrom the Department of Neurology, Wayne State University School of Medicine, Detroit, MI (H.S.).
Babak B NaviDepartment of Neurology (B.B.N., H.K.), Weill Cornell Medical College, New York, NY.
James C GrottaClinical Innovation and Research Institute, Memorial Hermann Hospital, Houston, TX (J.G.).
Hooman KamelDepartment of Neurology (B.B.N., H.K.), Weill Cornell Medical College, New York, NY.
Arvind BambhroliyaDepartment of Neurology, Institute for Stroke and Cerebrovascular Disease (A.B., F.S.V., S.I.S., L.M., S.A.S.), UT Health McGovern School of Medicine, Houston, TX.
Farhaan S VahidyDepartment of Neurology, Institute for Stroke and Cerebrovascular Disease (A.B., F.S.V., S.I.S., L.M., S.A.S.), UT Health McGovern School of Medicine, Houston, TX.
Peng Roc ChenDepartment of Neurosurgery (P.R.C., S.B.), UT Health McGovern School of Medicine, Houston, TX.
Spiros BlackburnDepartment of Neurosurgery (P.R.C., S.B.), UT Health McGovern School of Medicine, Houston, TX.
Sean I SavitzDepartment of Neurology, Institute for Stroke and Cerebrovascular Disease (A.B., F.S.V., S.I.S., L.M., S.A.S.), UT Health McGovern School of Medicine, Houston, TX.
Louise McCulloughDepartment of Neurology, Institute for Stroke and Cerebrovascular Disease (A.B., F.S.V., S.I.S., L.M., S.A.S.), UT Health McGovern School of Medicine, Houston, TX.
Sunil A ShethDepartment of Neurology, Institute for Stroke and Cerebrovascular Disease (A.B., F.S.V., S.I.S., L.M., S.A.S.), UT Health McGovern School of Medicine, Houston, TX.
Cornell University · USMemorial Hermann · USWayne State University · US

Funding

Role of Haptoglobin Genotype on Neuroinflammation and Coagulation Following Aneurysmal Subarachnoid HemorrhageK23NS106054 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BLACKBURN, SPIROS · 2018 to 2022
$875k
NINDS NIH HHS K23 NS106054
6 · The paper itself

Abstract

Background and Purpose- Recent landmark trials provided overwhelming evidence for effectiveness of endovascular stroke therapy (EST). Yet, the impact of these trials on clinical practice and effectiveness of EST among lower volume centers remains poorly characterized. Here, we determine population-level patterns in EST performance in US hospitals and compare EST outcomes from higher versus lower volume centers. Methods- Using validated diagnosis codes from data on all discharges from hospitals and Emergency Rooms in Florida (2006-2016) and the National Inpatient Sample (2012-2016) we identified patients with acute ischemic stroke treated with EST. The primary end point was good discharge outcome defined as discharge to home or acute rehabilitation facility. Multivariate regressions adjusted for medical comorbidities, intravenous tPA (tissue-type plasminogen activator) usage and annual hospital stroke volume were used to evaluate the likelihood of good outcome over time and by annual hospital EST volume. Results- A total of 3890 patients (median age, 73 [61-82] years, 51% female) with EST were identified in the Florida cohort and 42 505 (median age, 69 [58-79], 50% female) in the National Inpatient Sample. In both Florida and the National Inpatient Sample, the number of hospitals performing EST increased continuously. Increasing numbers of EST procedures were performed at lower annual EST volume hospitals over the studied time period. In adjusted multivariate regression, there was a continuous increase in the likelihood of good outcomes among patients treated in hospitals with increasing annual EST procedures per year (odds ratio, 1.1; 95% CI, 1.1-1.2 in Florida and odds ratio, 1.3; 95% CI, 1.2-1.4 in National Inpatient Sample). Conclusions- Analysis of population-level datasets of patients treated with EST from 2006 to 2016 demonstrated an increase in the number of centers performing EST, resulting in a greater number of procedures performed at lower volume centers. There was a positive association between EST volume and favorable discharge outcomes in EST-performing hospitals.

Indexed as

AgedAged, 80 and overBrain IschemiaCohort StudiesCross-Sectional StudiesEndovascular ProceduresEndpoint DeterminationFemaleFloridaHospitalizationHospital MortalityHumansMaleMiddle AgedPlasminogen ActivatorsPopulationPlasminogen Activatorsendovascular procedurespopulation healthprocedures and techniques utilizationstrokethrombectomy

Identifiers

PMID30726185
PMCPMC6407696
OpenAlexW2913906457

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.