Evidence map›Paper›PMID 30725237›Full record

ArticleEuropean journal of epidemiology2019

Nutritional epidemiology: forest, trees and leaves.

Edward Giovannucci

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Edward GiovannucciHarvard T.H. Chan School of Public Health, Boston, MA, USA. egiovann@hsph.harvard.edu.ORCID http://orcid.org/0000-0002-6123-0219

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ioannidis has stated that the field of nutritional epidemiology has generated confusion and numerous implausible findings and is in need of radical reform. One of the reforms he proposes is to conduct analyses that take into account the "totality for all nutritional factors measured". This approach is based on isolating and reducing diet into numerous independent variables with little regard to prior knowledge or the interrelations among dietary components, and relying on a "discovery" approach. This method, akin to genomewide association studies (GWAS), would involve very large sample sizes, small associations, no prior knowledge, and multiple testing considerations. This method is contrary to the more traditional hypothesis generating and testing approach built on all types of evidence. This commentary will contrast how suitable these two approaches are to study diet and disease.

Indexed as

Epidemiologic MethodsNutritional Physiological PhenomenaDietHumansCardiovascular diseasesDietEpidemiologyNutrition

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.