ArticleJournal of enzyme inhibition and medicinal chemistry2019
Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of candida β-carbonic anhydrase enzyme.
Article in Journal of enzyme inhibition and medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Biological investigation ofJournal of enzyme inhibition and medicinal chemistry · 2022Article
- Photodegradation and In Silico Molecular Docking Study of a Diuretic Drug: Clopamide.ACS omega · 2022Article
- Virtual screening based on molecular docking of possible inhibitors of Covid-19 main protease.Microbial pathogenesis · 2020Article
- Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors.International journal of molecular sciences · 2020Article
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6 authors.
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Abstract
Inhibition of the β-carbonic anhydrase (CA, EC 4.2.1.1) from pathogenic Candida glabrata (CgNce103) by 1H-indole-2,3-dione 3-[N-(4-sulfamoylphenyl)thiosemicarbazones] 4a-m was investigated. All the compounds were found to be potent inhibitors of CgNce103, with inhibition constants in the range of 6.4-63.9 nM. The 5,7-dichloro substituted derivative 4l showed the most effective inhibition (K
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