ArticleJournal of clinical hypertension (Greenwich, Conn.)2019
The interaction between hypertension and obstructive sleep apnea on subjective daytime sleepiness.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Sleep, Sleepiness, and Memory.Sleep science (Sao Paulo, Brazil) · 2024Article
- Review
- Sex-specific associations between daytime sleepiness, chronic diseases and mortality in obstructive sleep apnea.Frontiers in neuroscience · 2023Article
- Higher Hospital Frailty Risk Score Is an Independent Predictor of In-Hospital Mortality in Hospitalized Older Adults with Obstructive Sleep Apnea.Geriatrics (Basel, Switzerland) · 2022Article
- Epidemiology of obstructive sleep apnea: What is the contribution of hypertension and arterial stiffness?Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- The rate of decrease in oxygen desaturation during severe obstructive sleep apnea syndrome is correlated with subjective excessive daytime sleepiness.Sleep & breathing = Schlaf & Atmung · 2021Article
- Depression of Non-Neuronal Cholinergic System May Play a Role in Co-Occurrence of Subjective Daytime Sleepiness and Hypertension in Patients with Obstructive Sleep Apnea Syndrome.Nature and science of sleep · 2021Article
- Recent advances in the management of secondary hypertension-obstructive sleep apnea.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Review
- Clinical and polysomnographic features of hypertension in obstructive sleep apnea: A single-center cross-sectional study.Anatolian journal of cardiology · 2020Article
- The enigma of severe obstructive sleep apnea without sleepiness.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- The interaction between hypertension and obstructive sleep apnea on subjective daytime sleepiness.Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension is one of the most common chronic cardiovascular diseases in adults while obstructive sleep apnea (OSA) is the most common type of sleep apnea. It was recently reported that the mean Epworth Sleepiness Scale (ESS) score, measuring subjective daytime sleepiness, was significantly higher in non-hypertensive subjects than the hypertensive counterparts with moderate to severe obstructive sleep apnea. In the current study, the authors investigated the interaction between hypertension and OSA on daytime sleepiness among 280 subjects recruited from a sleep study. OSA was evaluated with the Apnea-Hypopnea Index (AHI), and daytime sleepiness was measured with the ESS. Significantly higher mean ESS scores were found for subjects without than those with hypertension (11.3 vs 9.4, P = 0.003) but only a marginally significant difference was discerned for the ESS scores between subjects with AHI ≥15/h and AHI <15/h (P = 0.075). A significant interaction between hypertension and OSA status on daytime sleepiness was observed from the analysis of variance (P = 0.02). The adjusted mean ESS score for the group of normotensive subjects with moderate to severe OSA (13.11) was significantly higher than the other three groups, namely, normotensive subjects with mild OSA (9.35), hypertensive subjects with mild OSA (9.70), and hypertensive subjects with moderate to severe OSA to (9.43). In conclusion, subjective daytime sleepiness of normotensive subjects with moderate to severe OSA was significantly more severe than other subjects.
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