SynthesisJournal of clinical hypertension (Greenwich, Conn.)2019
Orthostatic hypertension: From pathophysiology to clinical applications and therapeutic considerations.
Synthesis in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Drug-induced orthostatic hypotension: A systematic review and meta-analysis of randomised controlled trials.PLoS medicine · 2021Pooled it
- Orthostatic hypertension: From pathophysiology to clinical applications and therapeutic considerations.Journal of clinical hypertension (Greenwich, Conn.) · 2019Pooled it
- Association of orthostatic hypertension identified according to different definitions with cardiovascular disease. The PARTAGE study.Journal of hypertension · 2026Article
- Autonomic Cardiovascular Assessment in Obstructive Sleep Apnea Using Beat-to-Beat Blood Pressure: A Pilot Study.Sleep science (Sao Paulo, Brazil) · 2025Article
- Blood Pressure Postural Changes Variability Is Associated With Lower Cognition: The S.AGES Cohort.Journal of the American Heart Association · 2025Article
- Orthostatic and Standing Hypertension and Risk of Cardiovascular Disease.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Risk of Orthostatic Hypotension in Chronic Kidney Disease: A Community-Based Cohort Study.Kidney & blood pressure research · 2025Article
- Normative data for the 10-min lean test in adults without orthostatic intolerance.Frontiers in neurology · 2025Article
- Preclinical Orthostatic Abnormalities May Predict Early Increase in Vascular Stiffness in Different Age Groups: A Pilot Study.Diagnostics (Basel, Switzerland) · 2023Article
- Orthostatic Hypertension: A Newcomer Among the Hypertension Phenotypes.Hypertension (Dallas, Tex. : 1979) · 2023Review
- Exaggerated blood pressure response to standing in young-to-middle-age subjects: prevalence and factors involved.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Article
- A 3-year natural history of orthostatic blood pressure dysregulation in early Parkinson's disease.NPJ Parkinson's disease · 2023Article
- Predictors of blood pressure response to ultrasound renal denervation in the RADIANCE-HTN SOLO study.Journal of human hypertension · 2022Article
- Prevalence of orthostatic hypertension and its association with cerebrovascular diagnoses in patients with suspected TIA and minor stroke.BMC cardiovascular disorders · 2022Article
- Association of orthostatic blood pressure response with incident heart failure: The Framingham Heart Study.PloS one · 2022Observational
- Orthostatic hypertension and adverse clinical outcomes in adults and older people.Journal of geriatric cardiology : JGC · 2021Article
- Postural changes in blood pressure among patients with diabetes attending a referral hospital in southwestern Uganda: a cross-sectional study.BMC cardiovascular disorders · 2021Article
- Orthostatic Hypertension and Intensive Blood Pressure Control; Post-Hoc Analyses of SPRINT.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Heart rate and blood pressure response improve the prediction of orthostatic cardiovascular dysregulation in persons with chronic spinal cord injury.Physiological reports · 2020Article
- Orthostatic Hypertension in Children: An Update.Frontiers in pediatrics · 2020Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthostatic hypertension (OHT), that is, sustained increase in blood pressure after standing, is an increasingly recognized cardiovascular disorder having been examined in much fewer studies compared with orthostatic hypotension (OH). However, in both OHT and OH, dysfunction of the autonomous nervous system is considered to be the primary pathophysiological disturbance, while significant associations with essential hypertension have been observed. Although in many studies OHT has been related to subclinical or clinical target organ damage, there is also evidence denying such an association. Because OHT is defined variably across different studies, the comparison of relevant outcomes is at least problematic. Since evidence about OHT treatment is exclusively based on limited non-randomized studies, no specific recommendations have been developed. Therefore, both the prognostic role and the clinical significance of OHT remain largely undefined. The aim of the present review is to summarize the available evidence regarding the definition, diagnosis, pathophysiology, prognostic role and treatment of OHT and highlight potential clinical implications of this underestimated condition.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.