Evidence map›Paper›PMID 30724335›Full record

ArticleThe Australian & New Zealand journal of obstetrics & gynaecology2019

'Small cost to pay for peace of mind': Women's experiences with non-invasive prenatal testing.

Hilary Bowman-Smart, Julian Savulescu, Cara Mand, Christopher Gyngell, Mark D Pertile, Sharon Lewis, Martin B Delatycki

Open access · hybridAbstract read
In one paragraph

Article in The Australian & New Zealand journal of obstetrics & gynaecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 45 citations in OpenAlex.

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  16. Clinician views and experiences of non-invasive prenatal genetic screening tests in Australia.The Australian & New Zealand journal of obstetrics & gynaecology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Hilary Bowman-SmartMurdoch Children's Research Institute, Melbourne, Victoria, Australia.ORCID 0000-0002-2142-9696
Julian SavulescuMurdoch Children's Research Institute, Melbourne, Victoria, Australia.
Cara MandMurdoch Children's Research Institute, Melbourne, Victoria, Australia.
Christopher GyngellMurdoch Children's Research Institute, Melbourne, Victoria, Australia.
Mark D PertileMurdoch Children's Research Institute, Melbourne, Victoria, Australia.
Sharon LewisMurdoch Children's Research Institute, Melbourne, Victoria, Australia.
Martin B DelatyckiMurdoch Children's Research Institute, Melbourne, Victoria, Australia.
The University of Melbourne · AUMurdoch Children's Research Institute · AUUniversity of Oxford · GBVictorian Clinical Genetics Services · AU

Funding

The Wellcome Trust 203132
6 · The paper itself

Abstract

backgroundNon-invasive prenatal testing (NIPT) has been available in Australia on a user-pays basis since 2012. Since its introduction, it has grown in popularity as a screening method for fetal aneuploidy and may become publicly funded.

aimsTo assess the motivations and experiences of women who have undergone NIPT in a user-pays system in Australia. MATERIALS AND

methodsOne thousand women who had undergone NIPT through the Victorian Clinical Genetics Services in Melbourne, Australia were contacted and asked to complete a mixed-methods survey. The number of eligible responses received was 235. Quantitative data analysis was performed in STATA IC 15.1, and qualitative data were examined using content analysis.

resultsWomen reported generally positive experiences with NIPT and 95% of respondents indicated they would undergo NIPT in a future pregnancy. Most respondents received a low-risk result, with 2.2% receiving a high-risk result. Respondents viewed NIPT favourably compared to invasive testing and cited reassurance as a key reason they sought it. However, a small minority of women reported negative experiences with the testing process. Women were also supportive of NIPT becoming publicly funded, with 93% of respondents indicating support. Pre- and post-test counselling were identified as possible areas for improvement to ensure informed consent.

conclusionIn support of the existing literature, these results indicate that Australian women generally report positive experiences with NIPT. As NIPT becomes more common, with possible integration into public healthcare, further qualitative research would be valuable to examine the motivations and experiences of women undergoing NIPT.

Indexed as

AdolescentAdultAustraliaDecision MakingDown SyndromeFemaleGenetic TestingHealth ExpendituresHumansPregnancyPregnant PeoplePrenatal DiagnosisYoung Adultgenetic servicesgenetic testingpregnancyprenatal diagnosisprenatal screening

Identifiers

PMID30724335
PMCPMC6850570
OpenAlexW2911537107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.