Evidence map›Paper›PMID 30724156›Full record

ReviewEcoSal Plus2019

Mechanisms of Type I-E and I-F CRISPR-Cas Systems in

Chaoyou Xue, Dipali G Sashital

Open access · greenAbstract readReview
In one paragraph

Review in EcoSal Plus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Clonally relatedASM case reports · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Whole-genome sequencing ofMicrobiology resource announcements · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. TheEcoSal Plus · 2025
    Review
  14. Article
  15. Structural characterization of anti-CRISPR protein AcrIE9.Structural dynamics (Melville, N.Y.) · 2025
    Article
  16. Article
  17. Evolutionary trends inmSystems · 2025
    Article
  18. CRISPR-Cas Systems: A Functional Perspective and Innovations.International journal of molecular sciences · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chaoyou XueRoy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA.
Dipali G SashitalRoy J. Carver Department of Biochemistry, Biophysics & Molecular Biology, Iowa State University, Ames, IA.
Iowa State University · US

Funding

Defining CRISPR adaptation and interference mechanisms in E. coliR01GM115874 · NIGMS · IOWA STATE UNIVERSITY · PI SASHITAL, DIPALI GURUDUTT · 2016 to 2021
$1.5M
NIGMS NIH HHS R01 GM115874
6 · The paper itself

Abstract

CRISPR-Cas systems provide bacteria and archaea with adaptive immunity against invasion by bacteriophages and other mobile genetic elements. Short fragments of invader DNA are stored as immunological memories within CRISPR (clustered regularly interspaced short palindromic repeat) arrays in the host chromosome. These arrays provide a template for RNA molecules that can guide CRISPR-associated (Cas) proteins to specifically neutralize viruses upon subsequent infection. Over the past 10 years, our understanding of CRISPR-Cas systems has benefited greatly from a number of model organisms. In particular, the study of several members of the Gram-negative

Indexed as

CRISPR-Cas SystemsArchaeaBacteriophagesEnterobacteriaceaeEscherichia coliHost Microbial InteractionsPectobacterium

Identifiers

PMID30724156
PMCPMC6368399
OpenAlexW2913632015

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.