Evidence map›Paper›PMID 30724134›Full record

ArticleTissue engineering. Part C, Methods2019

Development of Modular, Dual-Perfused Osteochondral Constructs for Cartilage Repair.

Ethan L H Daley, Jochen Kuttig, Jan P Stegemann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering. Part C, Methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ethan L H Daley1 Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
Jochen Kuttig2 Faculty of Medicine, University of Tübingen, Tübingen, Germany.
Jan P Stegemann1 Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.

Funding

Structure, Composition, & Histology Core - Core BP30AR069620 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KARL J JEPSEN · 2016 to 2026
$8.4M
Bone Regeneration Using Osteogenic and Vasculogenic Tissue ModulesR01AR062636 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEGEMANN, JAN P. · 2014 to 2018
$1.7M
Modular Assembly of Interdigitated Osteochondral InterfacesR21AR062709 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEGEMANN, JAN P. · 2013 to 2014
$343k
NIAMS NIH HHS P30 AR069620NIAMS NIH HHS R01 AR062636NIAMS NIH HHS R21 AR062709
6 · The paper itself

Abstract

impact statementThis study describes methods for fabricating, culturing, and characterizing modular microbeads containing progenitor cells that can be used to create osteochondral tissue constructs. Such biphasic engineered tissues were cultured in a low flow rate perfusion bioreactor chamber to maintain tissue-specific differentiation while allowing development of the osteochondral interface.

Indexed as

ChondrogenesisOsteogenesisAnimalsAnimals, NewbornCartilage, ArticularCell DifferentiationCells, CulturedChondrocytesMesenchymal Stem CellsRats, Inbred F344Tissue Engineering3D cell culturebioreactorcartilagehydrogelsmesenchymal stem cellmodular tissue engineeringosteochondral

Identifiers

PMID30724134
PMCPMC6457327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.